Rabbit Anti-TM16J Polyclonal Antibody #abs130237

abs130237-50ug

1-2 Weeks

201

abs130237-100ug

1-2 Weeks

301

Description

May act as a calcium-activated chloride channel.

Other names

Anoctamin-9, also known as ANO9_HUMAN, is a transmembrane protein 16J that has been identified as a potential tumor protein p53-inducible protein 5. It is also referred to as p53-induced gene 5 protein or PIG5. ANO9_HUMAN has been found to be closely related to the TP53I5 gene, which is also associated with tumor suppression. The functions and mechanisms of ANO9_HUMAN in cellular processes are not yet fully understood, but ongoing research in this area may provide new insights into its potential role in tumor suppression and other biological activities.

Source

Rabbit

Specificity

TM16J Antibody detects endogenous levels of TM16J

Species Reactivity

Human

Application

ELISA (peptide) 1:20000-1:40000, IHC 1:50-1:200, and IF/ICC 1:100-1:500 are the recommended dilutions for various applications. These dilutions ensure optimal results based on the specific techniques used. ELISA with peptide antigens requires a higher dilution range compared to IHC and IF/ICC. It is important to use the appropriate dilution to achieve accurate and reliable experimental outcomes.

Immunogen

A synthesized peptide derived from human TM16J

Properties

Concentration

1mg/ml

Purification

Immunogen affinity purified

Clonality

Polyclonal Antibody

Stability & Storage

To maintain product integrity, it is recommended to store at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles.

Storage buffer

This product is Rabbit IgG in phosphate buffered saline with a pH of 7.4. It contains 150mM of NaCl, 0.02% sodium azide, and 50% glycerol. For optimal functionality, store at a temperature of -20 °C. This solution is stable for a period of 12 months from the date of receipt.

Target

Background

This protein exhibits calcium-dependent phospholipid scramblase activity, meaning it is capable of scrambling phosphatidylserine, phosphatidylcholine, and galactosylceramide. However, it does not possess calcium-activated chloride channel (CaCC) activity. Interestingly, it has the ability to inhibit the activity of ANO1.

Celluar localization

Plasma Membrane;

UniPort

A1A5B4