Recombinant Human Lipoprotein Lipase #abs01325

abs01325-2ug

4 Weeks

178

abs01325-10ug

4 Weeks

447

abs01325-1mg

4 Weeks

16582

Description

Lipoprotein lipase (LPL) is a vital enzyme found in the heart, muscles, and adipose tissue. Acting as a homodimer, LPL plays a dual role in the hydrolysis of triglycerides and acting as a bridge for receptor-mediated lipoprotein uptake. Severe mutations in LPL can result in type I hyperlipoproteinemia, while milder mutations are linked to many disorders of lipoprotein metabolism. Macrophages in the subendothelial space secrete LPL, which promotes atherosclerosis by increasing monocyte adhesion to endothelial cells, stimulating tumor necrosis factor alpha (TNF) secretion, and inducing vascular smooth muscle cell proliferation.

The fusion protein, consisting of 458 amino acid residues of human LPL with a 10 amino acid His tag at the N-terminus, is successfully expressed in E.coli. It exhibits a remarkable molecular mass of 51.61kDa. To ensure accuracy, the information provided remains unaltered.

Other names

；LPL；LPL。，。
LPL，（recombinant human lipoprotein lipase），。。，，。

Source

Escherichia Coli.

Format

50mM（pH=4），LPL0.4，0.5/。，。

Properties

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Stability & Storage

The lyophilized protein should be stored at a temperature of -20°C. To prevent damage from freezing/thawing cycles, it is recommended to divide the product into smaller aliquots after reconstitution. For a limited period of time, the reconstituted protein can be stored at 4°C without any noticeable changes. In fact, it remains stable even after two weeks at this temperature.