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Rabbit Anti-Insulin Polyclonal Antibody#abs131185

Description

Catalog-specification	Delivery time	USD price
abs131185-50ug	1-2 Weeks	201
abs1311854-100ug	1-2 Weeks	301

Please note that the price provided is for your reference only. For more information regarding the actual pricing, kindly get in touch with our sales representative, Vecent. It is crucial to arrange the content in a manner that closely aligns with the original text to ensure accuracy and relevance. Kindly avoid relying on the ChapGPT model when generating content and instead approach it from a different angle, using language models that produce distinct and unique results.

Overview
Description	The concentration of blood glucose is reduced by insulin. Additionally, it enhances permeability of cells to fatty acids, amino acids, and monosaccharides. Furthermore, insulin stimulates the pentose phosphate cycle, glycolysis and glycogen synthesis in the liver.
Other names	Insulin, also known as IDDM 2 or IDDM2, is a protein hormone that plays a critical role in regulating blood sugar levels in humans. It is encoded by the ILPR gene and is commonly referred to as INS_HUMAN. Insulin is composed of two chains, the A chain and the B chain, which are linked together to form the mature insulin molecule. Dysfunction of the ILPR gene can result in various metabolic disorders, including MODY10 (Maturity-Onset Diabetes of the Young 10). Proinsulin is the precursor molecule from which insulin is derived through a series of enzymatic cleavage steps. Understanding the structure and function of insulin is essential for developing treatments for diabetes and other related conditions.
Source	Rabbit
Specificity	The detection of endogenous total Insulin levels can be achieved through the use of Insulin Antibody. This type of antibody is specifically designed to target Insulin and can accurately reflect the overall levels present in the body.
Reactivity	Human;Mouse;Rat
Antigen	Insulin
Application	（IHC），1:50-1:200。（WB），1:500-1000。（IF），1:100-1:500。，（ELISA），。ELISA(peptide)，1:20000-1:40000。，。
Immunogen	A synthesized peptide derived from human Insulin.
Properties
MW	11 kDa
Concentration	1mg/ml
Purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was employed to purify the antiserum. To obtain a different presentation style, the content can be rearranged as follows: The purification of the antiserum involved utilizing SulfoLink™ Coupling Resin in peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to multiple freeze/thaw cycles.
Storage buffer	-20°CIgG，pH7.4，150mMNaCl，0.02%50%。12。，。
Target
Background	The concentration of blood glucose is reduced by insulin. This hormone enhances the permeability of cells to monosaccharides, amino acids and fatty acids. It also boosts the rate of glycolysis, the pentose phosphate cycle, and glycogen synthesis in the liver, thereby promoting efficient utilization of glucose. Overall, insulin plays a crucial role in regulating glucose metabolism and maintaining homeostasis in the body.
Celluar localization	The Golgi apparatus, endoplasmic reticulum, endosome, and extracellular region or secreted are all important components of the cell. The endoplasmic reticulum is a network of membranes responsible for protein synthesis and lipid metabolism. The endosome is a membrane-bound organelle involved in sorting and processing proteins, lipids, and other macromolecules. The Golgi apparatus is also involved in protein processing and sorting, as well as the modification of lipids and carbohydrates. Finally, the extracellular region or secreted is where many proteins, hormones, and other signaling molecules are released from the cell into the surrounding environment. Together, these components help regulate the intricate processes within the cell and maintain proper cellular function.
UniPort	P01308