Rabbit Anti-CKS2 Polyclonal Antibody #abs130462

abs130462-50ug

1-2 Weeks

201

abs130462-100ug

1-2 Weeks

301

Description

The essential role of the CKS2 protein lies in its binding to the catalytic subunit of cyclin-dependent kinases, which is crucial for their biological function. When examining CKS2 mRNA expression in HeLa cells, distinct patterns are observed throughout the cell cycle, indicating that the encoded protein serves a specialized role. By studying these expression patterns, researchers gain insight into the unique functions and regulation of CKS2 in cellular processes.

Other names

CDC28 protein kinase 2, also known as CDC28 or CKS2, is a regulatory subunit of the CDC28 protein kinase. CKS2 is the homolog of CKS1, a subunit of the Cdc28/Cdc2 kinase in Saccharomyces cerevisiae. It plays a crucial role in the regulation of cyclin-dependent kinases (CDKs). CDKs are essential for cell cycle progression and control various cellular processes. CKS2 is involved in the activation of CDKs and the regulation of cell cycle checkpoints. It is a key player in maintaining proper cell division and ensuring genomic stability. Understanding the functions and mechanisms of CDC28 protein kinase 2 is crucial for unraveling the intricate regulatory networks governing cell cycle progression.

Source

Rabbit

Specificity

CKS2 Antibody detects endogenous levels of CKS2

Species Reactivity

Human;Mouse

Application

IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Immunogen

A synthesized peptide derived from human CKS2

Properties

Concentration

1mg/ml

Purification

Immunogen affinity purified

Clonality

Polyclonal Antibody

Stability & Storage

To ensure optimal preservation, it is recommended to store at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the item to repeated cycles of freezing and thawing.

Storage buffer

Please note that the following content is generated based on the original information provided but in a completely different style:
To maintain the stability and integrity of the product, we recommend keeping the Rabbit IgG in phosphate buffered saline solution at a temperature of -20 °C. This specific formulation includes a pH level of 7.4, 150mM NaCl, 0.02% sodium azide, and a precise concentration of 50% glycerol.
Rabbit IgG in phosphate buffered saline is an ideal solution for various research applications. With the addition of glycerol, it ensures a controlled freezing environment at sub-zero temperatures. The pH level of 7.4 and the presence of 150mM NaCl contribute to the optimal conditions for the stability and functionality of the IgG.
It is essential to note that this product remains stable for a period of 12 months from the date of its receipt. After this duration, it is advised to consider obtaining a new supply to ensure the highest quality and effectiveness of your research.
To maintain the integrity of the Rabbit IgG, the addition of 0.02% sodium azide serves as a preservative in the solution. This compound prevents microbial growth and extends the shelf life of the product.
In conclusion, by storing the Rabbit IgG in phosphate buffered saline solution at -20 °C with the appropriate additives, such as glycerol and sodium azide, researchers can rely on a stable and effective antibody solution for their experiments.

Target

Background

The catalytic subunit of the cyclin-dependent kinases relies on its binding to carry out its vital biological function.

UniPort

P33552