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Rabbit Anti-GCYB1 Polyclonal Antibody #abs130464

Please note that the price provided above is only for your reference. For the detailed price, we kindly request you to get in touch with our seller, Vecent. We appreciate your understanding. Data Examples Western blot analysis on HuvEc cell lysate using GCYB1 Antibody This product is for...

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Description

Catalog-specification	Delivery time	USD price
abs130464-50ug	1-2 Weeks	201
abs130464-100ug	1-2 Weeks	301

Please note that the price provided above is only for your reference. For the detailed price, we kindly request you to get in touch with our seller, Vecent. We appreciate your understanding.

Overview
Description	The GUCY1B3 gene encodes a member of the adenylyl cyclase class-4/guanylyl cyclase family, which is essential in various biological processes. It forms a heterodimer consisting of an alpha and a beta chain. In humans, there are two isoforms of this protein produced as a result of alternative splicing. Understanding the functions and interactions of this protein can provide valuable insights into the regulation of physiological processes in the body.
Other names	There are various names for the guanylate cyclase enzyme, such as GC-S-beta-1, GC-SB3, GCbeta1, GCS beta 1, GCS beta 3, GCS-beta-1, GCS-beta-3, GCYB1_HUMAN, Guanylate cyclase soluble beta 1 chain, Guanylate cyclase soluble subunit beta-1, Guanylate cyclase soluble subunit beta-3, GUC1B3, GUCSB3, GUCY1B1, GUCY1B3, SGC, and Soluble guanylate cyclase small subunit. These different names refer to the same enzyme, which plays an important role in the body's signaling pathways. Despite the different names, the information they convey remains the same, and researchers continue to study the functions and properties of this fascinating enzyme.
Source	Rabbit
Specificity	GCYB1 Antibody detects endogenous levels of GCYB1
Species Reactivity	Human;Mouse;Rat
Application	The recommended dilutions for Western blot (WB) range from 1:500 to 1:2000. For immunohistochemistry (IHC), the optimal dilutions are 1:50 to 1:200. If you are performing immunofluorescence/immunocytochemistry (IF/ICC), dilute the antibodies in the range of 1:100 to 1:500. When conducting ELISA with peptide antigens, the suggested dilutions are between 1:20000 and 1:40000. It is important to adhere to these dilution ranges to achieve accurate and reliable results for your experiments.
Immunogen	A synthesized peptide derived from human GCYB1
Properties
Concentration	1mg/ml
Purification	Immunogen affinity purified
Clonality	Polyclonal Antibody
Stability & Storage	To maintain stability for a year, it is recommended to store the item at a temperature of -20 °C. It is crucial to avoid subjecting it to repeated freeze/thaw cycles.
Storage buffer	The rabbit IgG is suspended in a solution of phosphate buffered saline with a pH of 7.4, along with 150mM NaCl, 0.02% sodium azide and 50% glycerol. It should be stored at a temperature of -20°C for optimal longevity, and is stable for up to 12 months from the date of receipt.
Target
Background	cGMP，（NO）。
Tissue specificity	Proteins have been identified in the brain cortex and cerebellum, indicating their presence in these regions.
Celluar localization	Cytosol;Plasma Membrane;
UniPort	Q02153