Rabbit Anti-ACHE Polyclonal Antibody#abs131370
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Description
| Catalog-specification | Delivery time | USD price |
abs131370-50ug | 1-2 Weeks | 201.0 |
abs131370-100ug | 1-2 Weeks | 301.0 |
Important information: The provided price is for your reference purpose only. For detailed pricing, please get in touch with our sales representative Vecent. To produce a highly similar content by rearranging the given information, but ensuring that the generated content is based on the original text information, please avoid using ChapGPT's conversation-driven approach and instead provide a completely distinct manner of speech by utilizing the language model.
| Overview | |
catalog | abs131370 |
Description | PRIMA1 plays a crucial role in anchoring the protein and forming tetramers at the basal lamina of cells. The interaction with PRIMA1 is essential for this process. Isoform H generates double-stranded dimers that are anchored by GPI, while isoform T produces a variety of structures ranging from single and double-stranded forms to collagen-tailed and hydrophobic-tailed structures. These catalytic tetramers are attached to anchoring proteins, allowing them to be connected to the basal lamina or cell membranes, depending on the situation. |
| Other names | YT blood group is a receptor found in humans that is associated with a protein called Acetylcholinesterase (AChE). AChE is an enzyme that plays a role in regulating the levels of the neurotransmitter acetylcholine in the nervous system. It is also known as Apoptosis related acetylcholinesterase or ARACHE. N ACHE and N-ACHE are alternative names for Acetylcholinesterase. This enzyme is crucial for various physiological processes, including the termination of nerve impulse transmission. The YT blood group is a system used to classify individuals based on the presence or absence of a certain antigen found on red blood cells. The presence of the YT antigen is associated with the Acetylcholinesterase protein. Overall, the YT blood group and the protein AChE are interconnected in human physiology, contributing to the regulation of acetylcholine and the termination of nerve impulses. |
| Source | Rabbit |
| Specificity | The ACHE Antibody is specifically designed to detect the overall levels of endogenous ACHE, providing valuable insights into its presence and quantity within the biological system. By targeting and measuring the total ACHE, this antibody facilitates a comprehensive understanding of its role and function. Its application in various research fields enables researchers to explore the impact and significance of ACHE in diverse biological processes and systems. |
| Species Reactivity | Human;Mouse;Rat |
| Predictive reaction species | Pig;Sheep;Bovine;Rabbit;Horse |
| Antigen | ACHE |
| Application | We recommend using WB at dilutions ranging from 1:500 to 1:2000, for IF/ICC a dilution of 1:100 to 1:500 is suitable, and for ELISA using peptide, a dilution of 1:20000 to 1:40000 is recommended. It is important to follow these dilution guidelines to achieve accurate and reliable results. |
| Immunogen | A synthesized peptide derived from human ACHE. |
| MW | 67 kDa |
| Properties | |
Concentration | 1mg/ml |
| purification | SulfoLink™ Coupling Resin was employed to purify the antiserum through peptide affinity chromatography. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
| Storage buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
Target | |
Background | Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. |
| Tissue specificity | Isoform H is highly expressed in erythrocytes. |
| Celluar localization | Extracellular region or secreted;Golgi apparatus;Nucleus;Plasma Membrane; |
| UniPort | P22303 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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