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Rabbit Anti-INSIG2 Polyclonal Antibody#abs138510

Description

Catalog-specification	Delivery time	USD price
abs138510-100ug	1-2 Weeks	301.0
abs138510-50ug	1-2 Weeks	201.0

Please note that the price provided is only intended as a reference. For more detailed pricing information, we recommend contacting our sales representative, Vecent. It's essential to ensure that the content you generate is based on the original text and rearranged to produce highly similar content. We request that you avoid using ChapGPT to generate similar content and rather opt for a language model that produces drastically different text.

Overview
catalog	abs138510
Other names	INSIG2, also known as INSIG 2 or insulin induced gene 2, is a hypothetical protein that plays a role in cellular membranes. This membrane protein, also referred to as INSIG2 membrane protein, is involved in insulin-induced gene expression and regulation. Additionally, INSIG2 is associated with MGC26273, an insulin-induced protein 2. Collectively, these proteins contribute to various cellular processes and may hold potential significance in biological systems.
Source	Rabbit
Specificity	The INSIG2 Antibody has the ability to identify the overall levels of endogenous INSIG2 present in a sample. The content generated should closely reflect this statement, while varying the wording and structure of the original information.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Rabbit;
Antigen	INSIG2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human INSIG2.
MW	25 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we purified the antiserum through peptide affinity chromatography. Our method yielded a highly efficient purification process that resulted in a high-quality antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain its integrity, it is recommended to keep the product at a temperature of -20 °C for a period of one year. It is important to note that this should be done without exposing the product to repeated freeze/thaw cycles, as this could compromise its quality. So, make sure to handle and store the product appropriately in order to ensure its efficacy.
Storage buffer	-20°CIgGpH 7.4，150mMNaCl，0.02%50%。，12。，。
Target
Background	Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.
Celluar localization	Endoplasmic reticulum;
UniPort	Q9Y5U4