SIRT3 Polyclonal Antibody #abs117800

abs117800-50ul

In Stock

228

Other names

SIR2L3

Source

Rabbit

Species Reactivity

Human;Mouse;Rat

Application

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:100 - 1:200

Immunogen

SIRT3 is a protein found in humans that encompasses amino acids 200-300. A synthetic peptide can be created to mimic this specific sequence. This peptide is designed to be highly similar to the original SIRT3 protein, as it is based on the sequence of amino acids 200-300 from the NP_036371.1 protein.

Properties

：A-549、22Rv1、SW620、MCF-7、、、。。，。，。、。，。
，，ChapGPT。

Properties

Purification

Affinity purification

Clonality

Polyclonal Antibody

Isotype

IgG

Stability & Storage

Store at -20℃. Avoid freeze / thaw cycles.

Storage buffer

Store at -20℃. Avoid freeze / thaw cycles.
The pH of the buffer is 7.3 and it contains 0.02% sodium azide and 50% glycerol. The buffer solution is supplemented with sodium azide which makes up 0.02% of the content. Additionally, it consists of a high concentration of glycerol, accounting for 50% of the total mixture. The pH level of the buffer is maintained at 7.3 to ensure stability and functionality.

Target

Background

This particular gene is responsible for encoding a protein that falls under the sirtuin family - an assortment of proteins that are similar in structure to the yeast Sir2 protein. The sirtuin family comprises four classes and is defined by a sirtuin core domain. While the specific operations of human sirtuins have yet to be fully identified, the yeast sirtuin proteins are known to regulate epigenetic gene silencing and repress recombination of rDNA. Scientists postulate that the human sirtuins may act as internal regulatory proteins with mono-ADP-ribosyltransferase activity. This specific gene belongs to class I of the sirtuin family. Two diverse transcript variants, which encode different proteins, have been noted for this gene.

Celluar localization

Mitochondrion matrix

UniPort

Q9NTG7