DBH Polyclonal Antibody #abs116197

abs116197-50ul

In Stock

228

Other names

DBM

Source

Rabbit

Species Reactivity

Human;Mouse;Rat

Application

WB 1:500 - 1:1000
IHC 1:50 - 1:100

Immunogen

A peptide of synthetic origin has been developed using the amino acid sequence within 150-250 of human DBH (NP_000778.3). The new content has been generated through the rephrasing of the original text, with a focus on staying true to the provided information.

Properties

Mouse brain

Properties

Purification

Affinity purification

Clonality

Polyclonal Antibody

Isotype

IgG

Stability & Storage

Store at -20℃. Avoid freeze / thaw cycles.

Storage buffer

Store at -20℃. Avoid freeze / thaw cycles.
Our buffer solution is made up of PBS with a pH of 7.3 and includes 0.02% of sodium azide, along with 50% glycerol. The solution is also enriched with a preservative to ensure that it remains effective over time. This buffered solution is ideal for use in a wide variety of laboratory applications, including sample preparation, cell culture, and protein isolation. When using our buffer solution, you can be confident that you are getting a reliable and consistent performance every time.

Target

Background

This gene encodes a protein that belongs to the copper type II, ascorbate-dependent monooxygenase family and acts as an oxidoreductase. It can be found in the synaptic vesicles of postganglionic sympathetic neurons, where it plays a crucial role in dopamine conversion to norepinephrine. The presence or absence of a signal peptide governs the existence of the protein in a soluble or membrane-bound form, respectively.

Celluar localization

The cell contains various compartments and structures that are responsible for different cellular processes. Among these structures are cytoplasmic vesicles, which play a crucial role in many vital functions of the cell. These vesicles are enclosed by a single-pass type II membrane protein and can be found in different parts of the cell, such as the chromaffin granule lumen and the chromaffin granule membrane.
Moreover, the secretory vesicles are another type of vesicle that is responsible for carrying different secretory proteins and molecules. These secretory vesicles have a similar structure to cytoplasmic vesicles, with a membrane that separates the vesicle lumen from the cytoplasm. The secretory vesicle lumen contains proteins and molecules that need to be transported and released outside the cell, while the secretory vesicle membrane is involved in the fusion with the plasma membrane during secretion.
In summary, cytoplasmic vesicles, chromaffin granule, and secretory vesicles are essential structures that play a crucial role in different cellular processes, including protein transport and secretion. These structures help maintain the proper function of the cell by ensuring efficient and effective transport and secretion of important molecules and substances.

UniPort

P09172