Rabbit Anti-GATA6 Polyclonal Antibody#abs131366
Please note that the price mentioned above is only for your reference. If you wish to know the exact details of the pricing, we kindly request you to contact our seller Vecent. It is essential to understand that the information provided is tentative and subject to change, which is why we...
Description
| Catalog-specification | Delivery time | USD price |
abs131366-50ug | 1-2 Weeks | 201.0 |
abs131366-100ug | 1-2 Weeks | 301.0 |
Please note that the price mentioned above is only for your reference. If you wish to know the exact details of the pricing, we kindly request you to contact our seller Vecent. It is essential to understand that the information provided is tentative and subject to change, which is why we recommend getting in touch with our representative to obtain accurate details regarding the price.
| Overview | |
catalog | abs131366 |
Description | Terminal differentiation and/or proliferation are believed to play a crucial role in regulating various biological processes. |
| Other names | GATA binding factor 6, also known as GATA binding protein 6, or GATA-binding factor 6, is a transcription factor encoded by the GATA6 gene in humans. This protein, commonly referred to as Gata6, plays a crucial role in the regulation of gene expression. Gata6 is a highly conserved protein and is involved in various biological processes, including embryonic development, cell differentiation, and tissue-specific gene expression. Transcription factor Gata 6, or Transcription factor GATA-6, is another name for Gata6. It is responsible for binding to specific DNA sequences and controlling the transcription of target genes. Gata6 is expressed in a variety of tissues, including the heart, lung, pancreas, and intestine. Understanding the functions and mechanisms of Gata6 has significant implications for human health and disease. Studies have shown that alterations in the expression or activity of Gata6 can lead to developmental abnormalities and various disorders, such as congenital heart defects, gastrointestinal diseases, and certain types of cancer. In conclusion, Gata6, also known as GATA binding factor 6 or GATA-binding factor 6, is a critical transcription factor involved in the regulation of gene expression and plays a vital role in various biological processes and disease development. |
| Source | Rabbit |
| Specificity | Our GATA6 Antibody is designed to specifically recognize and measure the levels of total endogenous GATA6 protein. |
| Species Reactivity | Human;Mouse;Rat |
| Predictive reaction species | Xenopus;Zebrafish;Pig;Sheep;Chicken;Bovine; |
| Antigen | GATA6 |
| Application | The recommended dilution for Western blotting is 1:500-1:2000, for immunofluorescence/immunocytochemistry it is 1:100-1:500, and for ELISA using a peptide it is 1:20000-1:40000. |
| Immunogen | A synthesized peptide derived from human GATA6. |
| MW | 45 kDa |
| Properties | |
Concentration | 1mg/ml |
| purification | SulfoLink™ Coupling Resin was employed for peptide affinity chromatography to purify the antiserum. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To ensure the longevity of your product, it is recommended to store it at a temperature of -20 °C for a year. However, it is important to avoid exposing the product to repeated freeze/thaw cycles, as this can affect its quality. So, make sure to handle your product carefully and store it in optimal conditions for the best results. |
| Storage buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
Target | |
Background | Transcriptional activator (PubMed:19666519, PubMed:27756709, PubMed:22750565, PubMed:22824924). Regulates SEMA3C and PLXNA2 (PubMed:19666519). Involved in gene regulation specifically in the gastric epithelium (PubMed:9315713). May regulate genes that protect epithelial cells from bacterial infection (PubMed:16968778). Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (By similarity). Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). |
| Tissue specificity | Expressed in heart, gut and gut-derived tissues. |
| Celluar localization | Nucleus; |
| UniPort | Q92908 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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