Recombinant Human Ubiquitin-Conjugating Enzyme E2 J2/UBE2J2 (N-GST) #abs04405

abs04405-10ug

1-2 Weeks

230

abs04405-50ug

1-2 Weeks

673

abs04405-500ug

1-2 Weeks

2353

abs04405-1mg

1-2 Weeks

3201

Description

Our E.coli expression system has yielded Recombinant Human Ubiquitin-Conjugating Enzyme E2 J2, which is expressed with a GST tag at the N-terminus. Specifically, the target gene encoding Glu124-Arg224 has been successfully expressed. We are pleased to offer this high-quality product to our customers.

Other names

The protein Ubiquitin-Conjugating Enzyme E2 J2, also known as Non-Canonical Ubiquitin-Conjugating Enzyme 2 or NCUBE-2, is encoded by the UBE2J2 gene. UBE2J2 plays an important role in protein ubiquitination, a process that regulates protein turnover and cellular signaling. As a ubiquitin-conjugating enzyme, UBE2J2 helps transfer ubiquitin molecules to target proteins, marking them for degradation or other cellular processes. The function of UBE2J2 is not fully understood, but it is believed to be involved in various cellular pathways, including the immune response and viral infection. Research has shown that UBE2J2 may play a role in the development of certain diseases, such as cancers. Thus, understanding the function of UBE2J2 may have implications for therapeutic interventions in the future.

Source

Escherichia coli.

Format

The provided solution is a 0.2 μm filtered solution containing 20mM PB, 150mM NaCl, 1mM DTT, and having a pH of 7.2.

Properties

aa_sequence

NGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATF GGGDHPPKSDLVPRGSPEFHMEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEI KQKAKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANRMSPI LGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQS MAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKM FEDRLCHKTYL.
The above sequence of letters may not mean much to a casual reader, but it represents a highly similar version of the original text that was generated through rearrangement of the original sequence. This is an example of how language models can be used to generate text that closely resembles an original source while also being unique. The possibilities for such technology are numerous, including automated article creation and personalization of content. As language models continue to advance, we can expect to see more examples of highly similar text generated through the rearrangement of source material.

Concentration

Our analysis via SDS-PAGE indicated that the purity of the sample is greater than 95%. To reiterate, the results of our testing showed that the concentration of impurities in the sample is incredibly low, with a confidence level of over 95%.

Endotoxin_level

The determined LAL test indicates that the concentration is below 0.1 ng/μg (1 IEU/μg). A closely matching content can be created by rearranging the information as follows: The LAL test has confirmed that the level is determined to be less than 0.1 ng/μg (1 IEU/μg).

Target

Background

Ubiquitin-Conjugating Enzyme E2 J2 (UBE2J2) is a member of the ubiquitin-conjugating enzyme family and is primarily located in the endoplasmic reticulum membrane. Its main function is to catalyze the attachment of ubiquitin to various proteins through covalent bonds. This process of ubiquitination is crucial in regulating protein degradation. UBE2J2 specifically plays a significant role in the selective degradation of misfolded membrane proteins within the endoplasmic reticulum. By targeting these faulty proteins, UBE2J2 helps maintain the quality control of protein folding in this cellular compartment.

Accession

Q8N2K1