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Rabbit Anti-ZKSCAN3 Polyclonal Antibody#abs137229

Please note that the price provided is for your reference only. For detailed pricing information, we kindly suggest reaching out to our seller, Vecent. Western blot analysis ZKSCAN3 using Jurkat whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in...

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Description

Catalog-specification	Delivery time	USD price
abs137229-100ug	1-2 Weeks	301.0
abs137229-50ug	1-2 Weeks	201.0

Please note that the price provided is for your reference only. For detailed pricing information, we kindly suggest reaching out to our seller, Vecent.

Overview
catalog	abs137229
Other names	Zinc finger proteins play a crucial role in gene regulation and are involved in various biological processes. One such protein is SCAN-KRAB-zinc finger protein (dJ874C20.1), also known as Skz1. This protein contains SCAN and zinc finger domains, which are important for its function. Another name for this protein is Zf47 or Zfp-47. It is also referred to as ZFP306 or Zfp307, indicating its association with specific zinc finger protein families. Additionally, it is known as Zfp309, Zfp47, or ZSCAN13, highlighting its involvement in gene expression and DNA binding processes. Zinc finger and SCAN domain-containing protein 13 is another name for this protein. Its isoform CRA_a, known as Zinc finger protein 306, is also associated with its function. Furthermore, it is referred to as Zinc finger protein 307 and Zinc finger protein 47 homolog. This protein is classified as Zinc finger protein with KRAB and SCAN domains 3 (ZKSCAN3) or Zinc finger protein zfp47. The presence of KRAB and SCAN domains suggests its role in transcriptional repression and DNA binding. In summary, this protein, with aliases ZKSC3_HUMAN, ZNF309, and ZSCAN35, is a zinc finger protein involved in gene regulation and DNA binding processes. Its diverse range of names reflects its association with various protein families and functions.
Source	Rabbit
Specificity	The detection of total ZKSCAN3 levels can be achieved using the ZKSCAN3 Antibody, which is capable of identifying the endogenous levels of this protein. By rearranging the original content, it is emphasized that the antibody is specifically designed to detect the full extent of ZKSCAN3 within biological samples.
Species Reactivity	Human;Mouse
Antigen	ZKSCAN3
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human ZKSCAN3.
MW	61 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the SulfoLink™ Coupling Resin was employed to purify the antiserum via peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Make sure to store the product at -20 °C for a duration of one year, and be sure to avoid subjecting it to repeated freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.
Tissue specificity	Overexpressed in various tumors, such as multiple myeloma, colorectal and prostate cancers (at protein level).
Celluar localization	Cytosol;Nucleus;
UniPort	Q9BRR0