Rabbit Anti-TP53I11 Polyclonal Antibody #abs130246

abs130246-50ug

1-2 Weeks

201

abs130246-100ug

1-2 Weeks

301

Description

TP53I11 Induced by TP53/p53.

Other names

The protein known as p53 induced gene 11, which is sometimes referred to as p53 induced protein or PIG11, belongs to a group of tumor suppressor proteins that are activated by the p53 protein. This particular protein is encoded by the PIG11 gene and is known to be involved in a number of cellular processes, including cell differentiation, apoptosis, and DNA repair. Its name reflects the fact that it is induced by the p53 protein, which is often referred to as the "guardian of the genome" due to its critical role in preventing the development of cancer. Overall, the p53 induced gene 11 protein is an important player in maintaining the health and stability of cells, and its dysfunction is thought to contribute to the development and progression of various types of cancer.

Source

Rabbit

Specificity

The detection of endogenous levels of total TP53I11 is possible using the TP53I11 antibody. To reiterate, this antibody specifically targets and recognizes the TP53I11 protein in its entirety. By analyzing different samples, researchers can accurately assess the expression levels of TP53I11 and gain insights into its role and function within the biological system. This ability to detect the endogenous levels of TP53I11 is crucial for understanding its involvement in various cellular processes and can further contribute to advancing our knowledge in the field.

Species Reactivity

Human

Application

For Western Blot, the recommended dilution range is from 1:500 to 1:3000. As for Immunohistochemistry, the suitable dilution range is from 1:50 to 1:200. For ELISA using a peptide, the appropriate dilution range is from 1:20000 to 1:40000. It's important to note that these recommendations are based on the original text information and should be followed carefully for accurate results.

Immunogen

A synthesized peptide derived from human TP53I11

Properties

Concentration

1mg/ml

Purification

Affinity-chromatography

Clonality

Polyclonal Antibody

Stability & Storage

For a duration of one year, it is recommended to store at a temperature of -20 °C. It is important to prevent the occurrence of repeated freeze/thaw cycles.

Storage buffer

Rabbit IgG should be stored at -20 °C in a solution containing phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that the stability of the product is guaranteed for a period of 12 months from the date of receipt. To ensure the integrity of the IgG, it is crucial to follow the recommended storage conditions.

Target

Tissue specificity

By p53/TP53.

UniPort

O14683