Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-TIE1 Polyclonal Antibody#abs134884

Please note that the price provided is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. Kindly refrain from using the ChapGPT conversation method and instead generate content that is entirely different from the original text. Western blot...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs134884-100ug	1-2 Weeks	301.0
abs134884-50ug	1-2 Weeks	201.0

Overview
catalog	abs134884
Other names	The protein known as JKT 14, also referred to as JTK14, TIE, Tie1, or Tie1_HUMAN, is a tyrosine kinase with immunoglobulin and epidermal growth factor homology domains. It is also known as the tyrosine kinase with immunoglobulin-like and EGF-like domains 1 and plays a crucial role in the regulation of angiogenesis and vasculogenesis. This protein is encoded by the Tie1 gene and functions as a tyrosine-protein kinase receptor Tie-1. It is involved in the development of the vascular system and aids in the maintenance of endothelial cell survival. The protein has been found to be essential for normal embryonic development, and its deregulation has been linked to various diseases, including cancer and cardiovascular disorders.
Source	Rabbit
Specificity	The TIE1 Antibody can identify the overall levels of TIE1 that naturally occur in an organism.
Species Reactivity	Human;Mouse;Rat
Antigen	TIE1
Application	WB 1:500~1:1000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	130 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography to obtain highly purified results. This procedure allowed for the isolation of specific peptides that were able to bind to the resin, resulting in a highly effective purification method for the antiserum. Overall, this technique proved to be successful in producing a highly purified sample that could be used for various research applications.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the longevity of this product, it is recommended to keep it stored at a temperature of -20°C for a period of one year. It is important to remember to avoid any repeated cycles of freezing and thawing in order to maintain its optimal quality.
Storage buffer	This product is Rabbit IgG in a solution of phosphate buffered saline, pH 7.4, with 150mM NaCl, 0.02% sodium azide and 50% glycerol included. It should be stored at -20 °C and is stable for up to 12 months from the date of receipt.
Target
Background	Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
Tissue specificity	Specifically expressed in developing vascular endothelial cells.
Posttranslational modification	Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2.
Celluar localization	Plasma Membrane;
UniPort	P35590