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Rabbit Anti-TRAPPC3 Polyclonal Antibody#abs134871

Description

Catalog-specification	Delivery time	USD price
abs134871-100ug	1-2 Weeks	301.0
abs134871-50ug	1-2 Weeks	201.0

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Overview
catalog	abs134871
Other names	TRAPPC3, also known as BET3 homolog, is a subunit of the trafficking protein particle complex 3 (TRAPPC3) that is conserved from yeast to humans. Other names for TRAPPC3 include AU019197, MGC105948, RP23-118D1.2, and TPPC3_HUMAN. TRAPPC3 is an essential component of the TRAPP complex, which plays a critical role in intracellular membrane trafficking. Specifically, TRAPPC3 is involved in regulating the transport of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus. Research has shown that mutations in TRAPPC3 are associated with a variety of human diseases, including intellectual disability, developmental delay, and epilepsy. Understanding the function of TRAPPC3 and the TRAPP complex may therefore provide important insights into these and other related disorders. In summary, TRAPPC3 is a highly conserved protein that plays a critical role in intracellular membrane trafficking, and its dysfunction has been implicated in a range of human diseases.
Source	Rabbit
Specificity	The endogenous levels of total TRAPPC3 can be accurately detected using the TRAPPC3 Antibody. The antibody specifically recognizes and binds to TRAPPC3 protein, enabling the measurement of its presence in biological samples. This detection method provides valuable insights into the expression and regulation of TRAPPC3 in various cellular contexts. By analyzing the endogenous levels of total TRAPPC3, researchers can gain a deeper understanding of its role in cellular processes and potentially uncover new therapeutic targets.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Chicken;Rabbit;Pig;Dog;Bovine;Sheep;Horse;
Antigen	TRAPPC3
Application	To use our product for Western blotting, dilute it at a ratio of 1:500~1:1000. For immuno-fluorescence or immuno-cytochemistry, you should dilute it at a ratio of 1:100-1:500. Finally, when using it for ELISA with peptide, dilute it at a ratio of 1:20000-1:40000. Please follow these instructions to get the most accurate and reliable results possible.
Immunogen	A synthesized peptide.
MW	22 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was used for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the product's quality, keep it in a freezer at a temperature of -20 °C for up to a year. It's important to prevent the product from going through multiple freeze-thaw cycles to maintain its effectiveness.
Storage buffer	The storage solution for rabbit IgG includes phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C. This solution remains stable for a period of 12 months starting from the date of receipt. Please note that the manner of generating the content has been changed, as per your request.
Target
Background	May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Celluar localization	Cytosol;Endoplasmic reticulum;Golgi apparatus;
UniPort	O43617