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Rabbit Anti-PGD Polyclonal Antibody#abs140793

Description

Catalog-specification	Delivery time	USD price
abs140793-100ug	1-2 Weeks	301.0
abs140793-50ug	1-2 Weeks	201.0

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Overview
catalog	abs140793
Other names	The gene 0610042A05Rik is responsible for the production of the enzyme 6-phosphogluconate dehydrogenase, also known as 6PGD. This enzyme is involved in the metabolism of glucose within the body, specifically breaking down 6-phosphogluconate. The process of breaking down this compound involves the removal of a carboxyl group, hence the enzyme is also known as decarboxylating 6-phosphogluconate dehydrogenase. The 6PGD protein is encoded by the AU019875 gene in humans, also known as Pgd. It has been linked to various diseases including cancer and inflammation. The function of 6PGD in these diseases is not fully understood, but it is believed to play a role in regulating cellular metabolism and oxidative stress. Research has shown that variations in the 6PGD gene can affect the activity of the enzyme, leading to changes in glucose metabolism and potentially contributing to disease susceptibility. The OTTMUSP00000011754 and RP23-249G3.4 genes are also associated with 6PGD. Overall, 6PGD is an important enzyme in the body's metabolic processes and its function can have implications for health and disease.
Source	Rabbit
Specificity	Endogenous levels of total PGD can be detected by the PGD Antibody. You can generate highly similar content by rearranging the above content. It is essential to ensure that the generated content is based on the information provided in the original text.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Chicken;Rabbit;Zebrafish;Dog;Horse;Bovine;Sheep
Antigen	PGD
Application	The dilution ratio for western blotting is recommended to be between 1:500 and 1:1000. For immunofluorescence or immunocytochemistry, the recommended dilution range is 1:100 to 1:500. When performing ELISA with peptide antigens, it is advised to dilute the samples at a ratio of 1:20000 to 1:40000. These dilution guidelines ensure optimal signal detection and reduce background noise.
Immunogen	A synthesized peptide.
MW	40 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography was employed using SulfoLink™ Coupling Resin to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage of the product, it is recommended that you store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated freeze/thaw cycles, as this may compromise its quality and efficacy. Please take care to follow these storage guidelines carefully to ensure the product remains stable and effective over time.
Storage buffer	The provided content is about the storage instructions for Rabbit IgG in phosphate buffered saline. The antibody should be stored at -20°C and is stable for a period of 12 months from the date of receipt. The storage buffer contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol in phosphate buffered saline at a pH of 7.4.
Target
Background	Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH.
Celluar localization	Cytosol;Extracellular region or secreted;Nucleus;
UniPort	P52209