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Rabbit Anti-TOR1AIP1 Polyclonal Antibody#abs134870

Please note that the mentioned price is for your reference only. For detailed pricing information, we recommend contacting our seller, Vecent. Western blot analysis of extracts from 293 cells, Jurkat cells and HeLa cells, using TOR1AIP1 antibody. This product is for research use only, not for...

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Description

Catalog-specification	Delivery time	USD price
abs134870-100ug	1-2 Weeks	301.0
abs134870-50ug	1-2 Weeks	201.0

Please note that the mentioned price is for your reference only. For detailed pricing information, we recommend contacting our seller, Vecent.

Overview
catalog	abs134870
Other names	Lamin-associated protein 1B, also known as LAP1B or lamina associated polypeptide 1B, is a key protein that interacts with torsin A, a protein linked to various neurological disorders. LAP1B belongs to the LAP1 family, which also includes LAP1C, and is involved in regulating the nuclear envelope structure and function. TOIP1_HUMAN, or torsin A interacting protein 1, is another name for LAP1B and refers to its interaction with torsin A. This interaction is thought to be important for maintaining proper nuclear envelope dynamics and dysfunction in this pathway has been linked to diseases such as dystonia. Overall, LAP1B plays an important role in cellular function and is a promising target for therapeutic interventions in diseases involving nuclear envelope dysfunction.
Source	Rabbit
Specificity	The total TOR1AIP1 is detected by the TOR1AIP1 Antibody, which specifically targets the endogenous levels of TOR1AIP1. To generate a highly similar content, the rearranged information would be as follows: The TOR1AIP1 Antibody is designed to recognize and measure the endogenous levels of total TOR1AIP1.
Species Reactivity	Human
Antigen	TOR1AIP1
Application	The recommended dilution for Western Blot is 1:500 to 1:1000, whereas for IF/ICC it is 1:100 to 1:500. For ELISA using peptide, the suggested dilution range is 1:20000 to 1:40000. To ensure consistency with the original text information, the content has been rearranged while maintaining its essence.
Immunogen	A synthesized peptide.
MW	66 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we purified the antiserum through peptide affinity chromatography. This process resulted in a highly purified solution.
Clonality	Polyclonal Antibody
Stability & Storage	One year of storage at -20 °C is recommended, while avoiding repeated cycles of freezing and thawing. It is important to note that the original text information should be used as a basis for generating highly similar content, but with a different arrangement and wording. ChapGPT should not be used to generate content in the same way as the original text.
Storage buffer	This solution contains Rabbit IgG in a phosphate buffered saline with a pH of 7.4, 150mM NaCl, as well as 0.02% sodium azide and 50% glycerol. It should be stored at -20°C and is stable for up to 12 months from the date of receipt. Please ensure to follow proper storage guidelines to maintain optimal stability and functionality of the product.
Target
Background	Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.
Tissue specificity	Expressed in muscle, liver and kidney.
Celluar localization	Nucleus;
UniPort	Q5JTV8