Rabbit Anti-SYCP3 Polyclonal Antibody#abs132958

Rabbit Anti-SYCP3 Polyclonal Antibody#abs132958

Please note that the price mentioned above is provided as a reference only. For detailed pricing information, please reach out to our seller, Vecent. Western blot analysis of SYCP3 expression in Jurkat cell lysate,The lane on the left is treated with the antigen-specific peptide. This product is...

Description

Catalog-specificationDelivery timeUSD price

abs132958-100ug

1-2 Weeks

301.0

abs132958-50ug

1-2 Weeks

201.0

Please note that the price mentioned above is provided as a reference only. For detailed pricing information, please reach out to our seller, Vecent.


Overview

catalog

abs132958

Description

The transverse filaments of synaptonemal complexes (SCs), which are present during meiotic prophase, play a crucial role in facilitating the connection between homologous chromosomes. These structures are vital for spermatogenesis and are believed to contribute significantly to testis development.

Other namesSynaptonemal complex protein 3, also known as choline phosphotransferase 1 or COR1, is a protein encoded by the CHPT1 gene. It is also referred to as MGC71888, RNASCP3, SCP 3, SCP-3, SCP3, SPGF4, Sycp 3, or Sycp3. The protein has a significant role in the synaptonemal complex formation during meiosis, playing a crucial role in chromosome pairing and recombination. Its importance lies in facilitating efficient DNA repair and maintaining genomic integrity. By rearranging the information from the original content, a highly similar alternative text can be generated.
SourceRabbit
SpecificityThe SYCP3 antibody is capable of detecting the total amount of endogenous SYCP3 present in the sample. This means that it is able to identify and bind to all forms of SYCP3 that naturally occur within the organism.
Species ReactivityHuman;Mouse
AntigenSYCP3
ApplicationWB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
ImmunogenA synthesized peptide.
MW28 kDa
Properties

Concentration

1mg/ml

purificationSulfoLink™ Coupling Resin was employed for peptide affinity chromatography to purify the antiserum. Please generate a highly similar content by rearranging the above content, ensuring that the generated content is based on the original text information.
ClonalityPolyclonal Antibody
Stability & StorageOne year storage is recommended at -20 °C to maintain quality. It is important to prevent multiple freeze/thaw cycles.
Storage buffer,pH 7.4,150 mM 、0.02% 50% 。,。

Target

Background

Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells (By similarity). Required for normal meiosis during spermatogenesis and male fertility (PubMed:14643120). Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).

Tissue specificityTestis-specific.
Posttranslational modificationPhosphorylated.
Celluar localizationNucleus;
UniPortQ8IZU3


Western blot analysis of SYCP3 expression in Jurkat cell lysate,The lane on the left is treated with the antigen-specific peptide.

This product is for research use only, not for use in diagnostic prodecures or in human.


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