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Rabbit Anti-RAPH1 Polyclonal Antibody#abs139326

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Description

Catalog-specification	Delivery time	USD price
abs139326-100ug	1-2 Weeks	301.0
abs139326-50ug	1-2 Weeks	201.0

Overview
catalog	abs139326
Other names	Protein RMO1, also known as Ras-associated and pleckstrin homology domains-containing protein 1, is encoded by the gene RAPH1. It is located in the Amyotrophic lateral sclerosis 2 chromosomal region and is a candidate gene for Amyotrophic lateral sclerosis 2. Another candidate gene in this region is Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein. Additionally, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein and C730009O10Rik are also present in this region. Lamellipodin, PREL-2, and Proline-rich EVH1 ligand 2 are other proteins associated with this genomic region. These proteins play important roles in various cellular processes and may be involved in the development and progression of Amyotrophic lateral sclerosis 2. By rearranging the provided information and emphasizing the candidates for Amyotrophic lateral sclerosis 2, a new summary is created.
Source	Rabbit
Specificity	The RAPH1 Antibody is capable of identifying total RAPH1 present in the body. This detection is based on levels present within the body naturally, without any external influence.
Species Reactivity	Human
Antigen	RAPH1
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human RAPH1.
MW	135kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography. This method ensured that the resulting antiserum was highly pure and met all the required standards.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated cycles of freezing and thawing, as this could compromise its efficacy and stability. Proper storage conditions can help ensure the longevity and effectiveness of the product.
Storage buffer	The Rabbit IgG is stored in a solution of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol at a temperature of -20 °C. It remains stable for up to 12 months from the date of receipt. The contents of this solution can be rearranged to form a highly similar text based on the original information.
Target
Background	Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion.
Tissue specificity	Isoform RMO1-RAPH1 is ubiquitously expressed with highest levels in brain, heart, ovary and developing embryo. Isoform RMO1 is widely expressed with highest levels in liver. Low expression in B-cells.
Celluar localization	Cytoskeleton;Cytosol;Nucleus;Plasma Membrane;
UniPort	Q70E73