Rabbit Anti-SSTR1 Polyclonal Antibody#abs135455
Notice: the price mentioned above is just a rough estimate. To obtain the accurate cost, kindly get in touch with our sales representative, Vecent. Kindly note that the price may fluctuate depending on the requirements and customization needed for your order. This product is for research use...
Description
| Catalog-specification | Delivery time | USD price |
abs135455-100ug | 1-2 Weeks | 301.0 |
abs135455-50ug | 1-2 Weeks | 201.0 |
Notice: the price mentioned above is just a rough estimate. To obtain the accurate cost, kindly get in touch with our sales representative, Vecent. Kindly note that the price may fluctuate depending on the requirements and customization needed for your order.
| Overview | |
catalog | abs135455 |
| Other names | Receptor 1 for somatostatin, also known as somatostatin receptor 1 (SSTR1), is a member of the G-protein coupled receptor family. It is one of the isoforms of somatostatin receptor that plays a crucial role in signal transduction. This receptor, often referred to as SRIF 2 or SS-1-R, is encoded by the SSR1_HUMAN gene. SSTR1 is responsible for mediating the biological effects of somatostatin, a peptide hormone involved in the regulation of numerous physiological functions. By binding to somatostatin, this receptor initiates a cascade of events within the cell, leading to modulation of various cellular processes. The designation Sstr1 is commonly used to refer to somatostatin receptor type 1, emphasizing its specific role in somatostatin signaling. With its distinct expression pattern and signaling properties, SSTR1 contributes to the diverse actions of somatostatin in different tissues and organs. Understanding the functions and characteristics of SSTR1 is of great importance in the development of therapeutic strategies targeting somatostatin receptors. Its involvement in physiological processes and potential implications in disease make SSTR1 an attractive target for drug discovery and treatment interventions. |
| Source | Rabbit |
| Specificity | The SSTR1 Antibody is capable of detecting total SSTR1 levels within the endogenous system. To produce a similar content, the original text information needs to be rearranged without changing the essence of the communication. |
| Species Reactivity | Human;Mouse;Rat |
| Antigen | SSTR1 |
| Application | The recommended dilutions for WB are 1:500 to 1:1000, while IF/ICC dilutions range from 1:100 to 1:500. In ELISA using peptide, the recommended dilution is 1:20000 to 1:40000. It is important to adhere to these dilutions to get accurate and reliable results. |
| Immunogen | A synthesized peptide. |
| MW | 43 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | Using SulfoLink™ Coupling Resin, the purification of the antiserum was carried out through peptide affinity chromatography. Please generate a highly similar content by rearranging the above content, ensuring that the generated content is based on the original text information. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To ensure optimal preservation, it is recommended to store the product at a temperature of -20 °C for a duration of one year. It is essential to avoid exposing the product to repeated freeze/thaw cycles in order to maintain its integrity and consistency. Remember to take appropriate measures to safeguard the product and follow the storage instructions carefully. |
| Storage buffer | This product consists of Rabbit IgG dissolved in a solution of phosphate buffered saline with a pH of 7.4, 150mM NaCl, and 0.02% sodium azide. It also contains 50% glycerol to enhance stability during storage at -20 °C. The product is guaranteed to remain stable for 12 months from the date of receipt. |
Target | |
Background | Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na+/H+ exchanger via pertussis toxin insensitive G proteins. |
| Tissue specificity | Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach. |
| Celluar localization | Plasma Membrane; |
| UniPort | P30872 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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