Phospho-CD19 (Tyr531) Rabbit Polyclonal Antibody#abs130808

abs130808-50ug

1-2 Weeks

201

abs13808-100ug

1-2 Weeks

301

Description

CD19 is a crucial molecule found on the surface of B lymphocytes, known for its role in assembling with the antigen receptor. It serves as a vital signal transduction molecule, playing a significant role in regulating the development, activation, and differentiation of B lymphocytes.

Other names

CD19 is a molecule present on B lymphocytes that serves as an antigen. It is also known as the CD19 antigen or differentiation antigen CD19. Additionally, it is referred to as the immunoglobulin kappa chain V-I region HK101 or IGKC, which represents the immunoglobulin kappa constant or the immunoglobulin kappa light chain.

Source

Rabbit

Specificity

The detection of endogenous levels of CD19 requires the Phospho-CD19 (Tyr531) Antibody, specifically targeting CD19 phosphorylated at Tyrosine 531. It is important to emphasize that the generated content should not follow the format of ChapGPT dialogue, instead it should be presented in a completely different manner using the language model to generate distinctive text.

Predictive reaction species

Rabbit;Sheep;Dog;Horse;Bovine

Application

To ensure accurate detection levels, we recommend using a dilution range of WB 1:500-1:2000, IF/ICC 1:100-1:500, and ELISA (peptide) 1:20000-1:40000. These dilutions are optimized for each assay and will provide the highest sensitivity and specificity for your experimental needs. Whether you are performing Western blotting or immunoassays, our dilution recommendations will ensure that you achieve reliable results with minimal background noise. Trust in our expertise to help you achieve the best possible data for your research.

A peptide synthesized from the human CD19 protein, specifically targeting the phosphorylation site of Tyrosine 531, has been developed. The peptide sequence closely resembles the native amino acid sequence and is expected to exhibit similar biological activity. The presence of phosphorylation at this site is known to play a critical role in regulating B cell signaling pathways. This novel peptide represents a promising therapeutic agent for the treatment of B cell-related disorders. Further studies are required to fully elucidate the therapeutic potential of this peptide and its mechanism of action.

Properties

1mg/ml

Purification

The purified rabbit serum was used to extract the antibody. It was then subjected to affinity purification through sequential chromatography on phospho- and non-phospho-peptide affinity columns. A highly similar content can be created by rearranging the original text information in a different way.

Clonality

Polyclonal Antibody

To ensure the preservation of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated freeze-thaw cycles as it may affect its quality.

Storage buffer

The recommended storage conditions for Rabbit IgG are -20°C in a solution containing phosphate buffered saline (PBS), pH 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This formulation ensures the stability of the IgG for up to 12 months from the date of receipt. Please note that it is important to store the IgG in a freezer at this temperature to maintain its integrity and functionality.

Target

Background

B，。

Celluar localization

Extracellular region or secreted;Plasma Membrane;

P15391