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Rabbit Anti-AR-beta3 Polyclonal Antibody#abs140375

Please note that the price mentioned here is just for your reference. To get the detailed pricing information, kindly contact our seller, Vecent. Western blot analysis AR-beta3 using K562 whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specification	Delivery time	USD price
abs140375-100ug	1-2 Weeks	301.0
abs140375-50ug	1-2 Weeks	201.0

Please note that the price mentioned here is just for your reference. To get the detailed pricing information, kindly contact our seller, Vecent.

Overview
catalog	abs140375
Other names	The ADRB3 gene, also known as Adrenergic beta-3 receptor or B3AR, is responsible for encoding the beta-3 adrenoceptor or beta-3 adrenoreceptor protein in humans. This receptor is primarily found in adipose tissue and has been associated with metabolic disorders and obesity. Other aliases for ADRB3 include ADR B3, ADRB 3, ADRB3R, Beta 3AR, Beta-3 adrenoceptor, Beta-3 adrenoreceptor, and FLJ99960. By rearranging the original content, we can understand the significance of ADRB3 in regulating metabolic function and its potential applications in therapeutic interventions for metabolic diseases.
Source	Rabbit
Specificity	The detection of endogenous levels of total AR-beta3 is enabled by the AR-beta3 Antibody. Would you like me to provide more information about this antibody?
Species Reactivity	Human
Predictive reaction species	Pig;Horse;
Antigen	AR-β3
Application	The recommended dilutions for WB, IHC, IF/ICC, and ELISA (peptide) are as follows: - For WB, a dilution of 1:1000 is suggested. - For IHC, a dilution of 1:200 is recommended. - For IF/ICC, a dilution range of 1:100-1:500 is advised. - For ELISA using peptides, dilutions ranging from 1:20000 to 1:40000 are recommended. These dilutions are critical in determining optimal signal-to-noise ratios and obtaining accurate and reliable results for various analytical techniques. Proper dilution ensures that the primary antibody binds specifically to the target molecule, while minimizing non-specific binding and background signal. It is essential to follow these dilution guidelines to achieve successful immunostaining or detection of the target of interest. Deviating from the recommended dilutions may result in compromised data quality and unreliable experimental outcomes.
Immunogen	A synthesized peptide derived from human AR-beta3.
MW	36kDa
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was used to purify the antiserum. This process ensured that the purified antiserum remains highly effective in its intended application. The affinity chromatography technique, coupled with the SulfoLink™ Coupling Resin, was essential in isolating the desired antibodies from contaminating impurities. As a result, the purified antiserum meets the stringent quality requirements for reliable use in various biomedical applications.
Clonality	Polyclonal Antibody
Stability & Storage	Make sure to store the product at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to multiple freeze/thaw cycles.
Storage buffer	Store the Rabbit IgG in phosphate buffered saline, pH 7.4, with a concentration of 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C. This product has a shelf life of 12 months from the date of receipt.
Target
Background	Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Tissue specificity	Expressed mainly in adipose tissues.
Celluar localization	Nucleus;Plasma Membrane;
UniPort	P13945