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Rabbit Anti-RYK Polyclonal Antibody#abs137869

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Description

Catalog-specification	Delivery time	USD price
abs137869-100ug	1-2 Weeks	301.0
abs137869-50ug	1-2 Weeks	201.0

Overview
catalog	abs137869
Other names	Protein kinase D3S3195, also known as ERK 3, is a hydroxyaryl protein kinase. It is also referred to as JTK 5, JTK 5A, or JTK5A protein tyrosine kinase. Another name for this kinase is receptor-like tyrosine kinase. The precursor form of this receptor-like tyrosine kinase is called RYK 1 or Ryk. In the human body, it is encoded by the RYK_HUMAN gene. The full name of this kinase is Tyrosine protein kinase RYK, and its precursor form is called Tyrosine protein kinase RYK precursor. Its alternative abbreviation is Tyrosine-protein kinase RYK. This protein kinase is also known by the name Vik.
Source	Rabbit
Specificity	The RYK Antibody is capable of detecting the total RYK protein at its endogenous levels. By arranging the provided information, the generated content is similar but in a different format.
Species Reactivity	Human
Predictive reaction species	Zebrafish;Chicken;Rabbit;Xenopus;Dog;Horse;Bovine;Sheep;Pig
Antigen	RYK
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human RYK.
MW	68 kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage, it is recommended that you keep the product at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated freeze-thaw cycles, as this may compromise its stability and quality over time. Taking these precautions will help to preserve the product's effectiveness and potency for longer periods of time.
Storage buffer	Our inventory includes Rabbit IgG in phosphate buffered saline with a pH of 7.4, 150mM NaCl, and 0.02% sodium azide. It is supplemented with 50% glycerol for better stability. To preserve its quality, we recommend storing it at -20 °C. This product has a shelf life of 12 months from the date of receipt, ensuring its effectiveness for an extended period.
Target
Background	May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Tissue specificity	Observed in all the tissues examined.
Posttranslational modification	Proteolytically cleaved, in part by presenilin, in response to WNT3 stimulation. Cleavage occurs during neuronal differentiation.
Celluar localization	Nucleus;Plasma Membrane;
UniPort	P34925