Rabbit Anti-RAMP2 Polyclonal Antibody#abs136693

Rabbit Anti-RAMP2 Polyclonal Antibody#abs136693

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Description

Catalog-specificationDelivery timeUSD price

abs136693-100ug

1-2 Weeks

301.0

abs136693-50ug

1-2 Weeks

201.0

Please note that the price mentioned here is only for your reference. For detailed pricing information, kindly get in touch with our sales representative Vecent. It's crucial to understand that the content generated should not be based on the ChapGPT dialogue generation method, but instead, should be entirely different using language model text generation.


Overview

catalog

abs136693
Other namesCalcitonin Receptor-Like Receptor Activity-Modifying Protein 2, also known as RAMP2, is a protein that plays an important role in regulating the activity of the calcitonin receptor. This receptor is involved in a number of important physiological processes, including blood pressure regulation, sensory perception, and bone development.
RAMP2 is also known as Receptor Activity Modifying Protein 2, and has two isoforms. It is encoded by the genes OTTMUSP00000002615 and OTTMUSP00000037624. Another name for RAMP2 is Receptor (Calcitonin) Activity Modifying Protein 2.
This protein is involved in transmitting signals from the calcitonin receptor to other parts of the cell, and in modulating the receptor's sensitivity to calcitonin and other ligands. In addition, RAMP2 has been linked to a number of diseases, including hypertension, osteoporosis, and chronic pain.
Overall, RAMP2 is an important protein involved in the regulation of a range of physiological processes, and its activity may be modified in a number of different disease states. Further research is needed to fully understand the role of RAMP2 in health and disease.
SourceRabbit
SpecificityThe RAMP2 Antibody is capable of identifying total RAMP2 levels that are present within the organism. It is designed to detect these endogenous levels of RAMP2 and has the ability to deliver an accurate estimate of the total amount of RAMP2 that is present. This makes the RAMP2 Antibody an essential tool in the detection and monitoring of RAMP2 levels. Whether you are studying cell signaling, gene expression, or protein structure, the RAMP2 Antibody is a powerful and reliable tool that can deliver rapid, accurate results.
Species ReactivityHuman;Mouse;Rat
AntigenRAMP2
ApplicationWB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
ImmunogenA synthetic peptide of human RAMP2.
MW20kD
Properties

Concentration

1mg/ml

purificationPeptide affinity chromatography using SulfoLink™ Coupling Resin was utilized to purify the antiserum. This resulted in a highly effective and specific purification process, which ensured the optimum quality of the final product. The method is widely recognized for its ability to bind and purify target molecules with exceptional precision, making it an ideal choice for the purification of antiserum. As a result, the purified antiserum is of the highest quality, suitable for use in a wide range of applications.
ClonalityPolyclonal Antibody
Stability & StorageTo maintain the quality of the product, it is advisable to store it at a temperature of -20°C for up to a year. It is important to avoid exposing it to repeated freeze and thaw cycles, which could compromise the integrity of the product. Therefore, it is recommended to handle the product with care and follow the storage instructions strictly. By doing so, the product will remain effective and safe for use during the entire storage duration.
Storage bufferThe solution containing Rabbit IgG is formulated in a phosphate buffered saline, at a pH value of 7.4, with 150mM NaCl and 0.02% of sodium azide. The solution is supplemented with 50% glycerol for enhanced stability and is recommended to be stored at a temperature of -20 °C. This Rabbit IgG solution is expected to remain stable for up to 12 months from the date of receipt.

Target

Background

Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.

Tissue specificityStrongly expressed in lung, breast, immune system and fetal tissues.
Celluar localizationLysosome;Plasma Membrane;
UniPortO60895



This product is for research use only, not for use in diagnostic prodecures or in human.


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