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Rabbit Anti-ACSL6 Polyclonal Antibody#abs141221

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Description

Catalog-specification	Delivery time	USD price
abs141221-100ug	1-2 Weeks	301.0
abs141221-50ug	1-2 Weeks	201.0

Overview
catalog	abs141221
Other names	The ACS2 gene encodes for Acyl CoA synthetase long chain family member 6, also known as FACL6 or Long Chain acyl CoA synthetase 6. This enzyme plays a crucial role in the activation of long chain fatty acids during their metabolism. Other names for this enzyme include LACS 6, LACS2, LACS5, and Long fatty acyl CoA synthetase 2. The function of ACS2 is to catalyze the transfer of an acyl group from ATP to fatty acids, forming a fatty acyl-CoA. This process is necessary for the breakdown of these fatty acids through β-oxidation, which occurs in the mitochondria. ACS2 is expressed in a variety of tissues, including liver and adipose tissue, where fatty acid metabolism is particularly active. Mutations in the ACS2 gene have been associated with a range of metabolic disorders, including insulin resistance, obesity, and type 2 diabetes. These disorders are characterized by an impairment in the metabolism of fatty acids, which can lead to an accumulation of fatty acids in the blood and tissues. In summary, ACS2 is an important enzyme involved in fatty acid metabolism, and its dysfunction can contribute to the development of metabolic disorders. Understanding the role of ACS2 in these disorders may lead to new strategies for their prevention and treatment.
Source	Rabbit
Specificity	The endogenous levels of total ACSL6 can be accurately recognized by the ACSC6 Antibody. To create a similar but distinctly rearranged content based on the original text, we may say: The ACSC6 Antibody is capable of detecting the total ACSL6 found naturally within an organism.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Horse;Dog;
Antigen	ACSL6
Application	(IF)(ICC)1:1001:500。(WB)1:5001:1000。(ELISA)1:200001:40000。，。
Immunogen	A synthesized peptide.
MW	78 KD
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography to purify the antiserum. Please provide an alternative rendition of the given information, while maintaining the same context and essence of the original text.
Clonality	Polyclonal Antibody
Stability & Storage	Make sure to store the item at a temperature of -20 °C for a duration of one year. It is essential to avoid subjecting the item to multiple freeze/thaw cycles.
Storage buffer	The storage condition for Rabbit IgG is as follows: it should be stored at -20 °C in phosphate buffered saline with a pH of 7.4. The solution should also contain 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is stable for a period of 12 months from the date of receipt. Please note that the generated content should be based on the original text information but with a significantly different presentation style.
Target
Background	Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
Tissue specificity	Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain.
Celluar localization	Endoplasmic reticulum;Mitochondrion;Peroxisome;Plasma Membrane;
UniPort	Q9UKU0