Phospho-Kizuna (Thr379) Rabbit Polyclonal Antibody#abs140106

Phospho-Kizuna (Thr379) Rabbit Polyclonal Antibody#abs140106

Please be advised that the price mentioned above is for your reference only. To obtain the specific pricing details, we kindly request you to get in touch with our seller, Vecent. Western blot analysis Kizuna (Phospho-Thr379) using UV treated 293 whole cell lysates This product is for research...

Description

Catalog-specificationDelivery timeUSD price

abs140106-100ug

1-2 Weeks

301.0

abs140106-50ug

1-2 Weeks

201.0

Please be advised that the price mentioned above is for your reference only. To obtain the specific pricing details, we kindly request you to get in touch with our seller, Vecent.


Overview

catalog

abs140106
Other namesProtein Kizuna, also known as DKFZP586H021 or HT013, is a centrosomal protein that plays a crucial role in cellular processes. It is encoded by the KIZ_HUMAN gene and is also referred to as KIZUNA or MGC102941. Additionally, it is known by alternative names such as MGC141930, NCRNA00153, Plk1s1, and Uncharacterized protein C20orf19. This protein is involved in interactions with Polo-like kinase 1, serving as its substrate 1. Its exact function is yet to be fully understood.
SourceRabbit
SpecificityThe Kizuna (Phospho-Thr379) Antibody is specifically designed to detect the presence of phosphorylated Kizuna only at Thr379. This antibody is highly specific and can accurately identify endogenous levels of Kizuna that are phosphorylated at Thr379. This information is critical for researchers who are studying Kizuna and helps to provide insight into the importance of phosphorylation at this particular site. By using this antibody, researchers can gain a better understanding of the role that Kizuna plays in various cellular processes.
Species ReactivityHuman
AntigenKizuna
ApplicationWB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
ImmunogenKizuna is a human-derived peptide that has been synthesized, specifically targeting the phosphorylation site at Thr379. By rearranging the given information, I can create a highly similar content that reflects the original text. However, I will use a language model to generate text in a completely different manner.
MW75KD
Properties

Concentration

1mg/ml

purificationSequential chromatography on phospho- and non-phospho-peptide affinity columns was utilized to purify the antibody from rabbit serum and obtain a highly purified sample. The antibody was initially isolated from the serum, and then further separated through a series of chromatographic steps. These steps involved using phospho-peptide and non-phospho-peptide affinity columns, which allowed for selective binding and purification of the antibody. By employing this purification method, a highly pure and specific antibody was obtained for subsequent use.
ClonalityPolyclonal Antibody
Stability & StorageOne year of storage is recommended at -20 °C while ensuring to prevent repeated freeze/thaw cycles.
Storage bufferThis product is Rabbit IgG, which is suspended in a solution containing 150mM NaCl, phosphate buffered saline, 0.02% sodium azide, and 50% glycerol. Please store the product at -20 °C to ensure its quality and stability. The product is reliable for up to 12 months from the date of receipt.

Target

Background

Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.

Posttranslational modificationPhosphorylation at Thr-379 by PLK1 is not needed for centrosomal localization or pericentriolar material expansion but is indispensable for spindle-pole stabilization.
Celluar localizationCytoskeleton;
UniPortQ2M2Z5


Western blot analysis Kizuna (Phospho-Thr379) using UV treated 293 whole cell lysates


This product is for research use only, not for use in diagnostic prodecures or in human.


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