Rabbit Anti-Prostacyclin Receptor Polyclonal Antibody#abs135445
Please note that the price provided above is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. Western blot analysis of extracts from K562 cells, using Prostacyclin Receptor antibody. This product is for research use only, not for use in...
Description
| Catalog-specification | Delivery time | USD price |
abs135445-100ug | 1-2 Weeks | 301.0 |
abs135445-50ug | 1-2 Weeks | 201.0 |
Please note that the price provided above is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent.
| Overview | |
catalog | abs135445 |
| Other names | The IP or prostacyclin receptor (PGI receptor) is also known as the Prostaglandin I2 receptor (PGI2 receptor) or Prostanoid IP receptor. Its biological function is to bind to Prostaglandin I2 (prostacyclin) and regulate vasodilation and platelet aggregation. The gene encoding this receptor is known as PI2R_HUMAN or Ptgir. Another common name for this receptor is PRIPR. |
| Source | Rabbit |
| Specificity | The Prostacyclin Receptor Antibody is designed to identify the total Prostacyclin Receptor at its natural levels. This antibody can detect the endogenous levels of the receptor with high specificity. The Prostacyclin Receptor Antibody is an essential tool, particularly in detecting and identifying the receptor's total population in various biochemical processes. With its accurate and reliable performance, this antibody is ideal for use in various applications, including research and diagnostics. Its effectiveness in detecting total Prostacyclin Receptor makes it one of the most sought after antibodies in biology and medical sciences. |
| Species Reactivity | Human |
| Antigen | Prostacyclin Receptor |
| Application | Based on the provided information, the recommended dilution ranges for WB (Western blot) are 1:500 to 1:1000, for IF/ICC (immunofluorescence/immunocytochemistry) are 1:100 to 1:500, and for ELISA using a peptide are 1:20000 to 1:40000. It is important to ensure proper dilutions for accurate and reliable results in these experimental techniques. |
| Immunogen | A synthesized peptide. |
| MW | 45 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To maintain the quality of this product, it is highly recommended to store it at a temperature of -20°C for a period of one year. Avoid exposing it to repeated freeze-thaw cycles, as this may alter its composition and effectiveness. Take good care of this product to ensure its longevity and maximum efficacy. |
| Storage buffer | The recommended storage condition for Rabbit IgG is to store it at -20 °C. It is formulated in phosphate buffered saline with a pH of 7.4 and contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This formulation ensures the stability of the product for 12 months from the date of receipt. |
Target | |
Background | Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase. |
| Posttranslational modification | Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling.Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. |
| Celluar localization | Cytosol;Plasma Membrane; |
| UniPort | P43119 |
Western blot analysis of extracts from K562 cells, using Prostacyclin Receptor antibody.
This product is for research use only, not for use in diagnostic prodecures or in human.
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