Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-PKR1 Polyclonal Antibody#abs135446

Dear valued customer, please note that the price provided is for reference only. For the detailed price, please contact our experienced seller, Vecent. We kindly urge you to get in touch with Vecent to receive accurate pricing information. Thank you for considering our services. Western blot...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs135446-100ug	1-2 Weeks	301.0
abs135446-50ug	1-2 Weeks	201.0

Overview
catalog	abs135446
Other names	The EG-VEGF receptor also goes by the name prokineticin receptor 1, or PROKR1, and is a type of G protein coupled receptor. Its gene is associated with two other names for the receptor, G protein coupled receptor 73 (GPR73) and G protein coupled receptor ZAQ. PK-R1 is another common abbreviation used. The receptor plays an important role in various physiological processes, including circadian rhythm regulation, pain perception, and angiogenesis. It binds to the prokineticin ligand, which initiates downstream signaling cascades to elicit cellular responses. Understanding the mechanisms underlying the function of the EG-VEGF receptor is of significant interest to researchers, particularly in the fields of cancer research and drug discovery. Targeting this receptor may offer promising therapeutic opportunities for various disorders where it is found to play a role.
Source	Rabbit
Specificity	The detection of total PKR1 levels is possible with the PKR1 Antibody, as it specifically targets the endogenous PKR1 protein.
Species Reactivity	Human;Mouse;Rat
Antigen	PKR1
Application	Here are some examples of highly similar content generated by rearranging the original text: - To conduct Western Blotting, dilute the primary antibody at a ratio of 1:500 to 1:1000. For IF/ICC experiments, dilute the primary antibody at a ratio of 1:100 to 1:500. Lastly, for ELISA experiments using peptides, dilute the antibody at a ratio of 1:20000 to 1:40000. - If you're performing Western Blotting, you'll need to dilute your primary antibody at a ratio of 1:500 to 1:1000. For IF/ICC assays, dilute your primary antibody at a ratio of 1:100 to 1:500. And when working with peptides in ELISA experiments, dilute the antibody at a ratio of 1:20000 to 1:40000. - For your Western Blotting experiments, use a dilution ratio of 1:500 to 1:1000 for the primary antibody. In IF/ICC studies, you'll want to dilute the primary antibody at a ratio of 1:100 to 1:500. And if you're doing ELISA experiments with peptides, dilute the antibody at a ratio of 1:20000 to 1:40000.
Immunogen	A synthesized peptide.
MW	45 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum went through peptide affinity chromatography for purification purposes. A highly similar content can be generated by rearranging the original text, while maintaining key information and sentence structure.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain quality, it is recommended to store at -20 °C for a period of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles.
Storage buffer	The solution contains Rabbit IgG in a phosphate buffered saline with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store the solution at a temperature of -20°C and it is stable for up to 12 months from the date of receipt.
Target
Background	Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy.
Tissue specificity	Localizes to glandular epithelium, stroma and vascular endothelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the stomach, throughout the small intestine, colon, rectum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary, brain, spleen, prostate and pancreas.
Celluar localization	Plasma Membrane;
UniPort	Q8TCW9