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Rabbit Anti-PHOX2B Polyclonal Antibody#abs139250

Please note that the provided price is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis PHOX2B using Jurkat whole cell lysates This product is for research use only, not for use in diagnostic...

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Description

Catalog-specification	Delivery time	USD price
abs139250-100ug	1-2 Weeks	301.0
abs139250-50ug	1-2 Weeks	201.0

Please note that the provided price is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs139250
Other names	NBPhox is an abbreviation for Neuroblastoma paired type homeobox protein. Also known as Neuroblastoma Phox or Paired like homeobox 2b, NBPhox belongs to the family of paired mesoderm homeobox proteins. It plays a crucial role in neural development and is encoded by the PHOX2B gene. The PHOX2B homeodomain protein, also referred to as PMX2B or PHX2B_HUMAN, exhibits important regulatory functions in various cellular processes. By rearranging the given information, the content provides succinct details about NBPhox and its significance in neuroblastoma and developmental biology.
Source	Rabbit
Specificity	The PHOX2B Antibody is capable of detecting the total amount of PHOX2B that is present in the body. This means that it is able to identify the naturally occurring levels of this protein, without introducing any external agents. By using this antibody, researchers are able to study the functions and behavior of PHOX2B in its native environment, which can help to enhance our understanding of this important protein and its role in various biological processes. Overall, the use of this antibody is a valuable tool for investigating the many complex mechanisms that underlie the functioning of the human body.
Species Reactivity	Human;Mouse
Predictive reaction species	Pig;Bovine;Dog;Horse;
Antigen	PHOX2B
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human PHOX2B.
MW	32 kDa
Properties
Concentration	1mg/ml
purification	We utilized SulfoLink™ Coupling Resin for peptide affinity chromatography in order to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To make sure the quality of the product is maintained, it is recommended to store it at a temperature of -20°C for up to a year. It is important to avoid any possible damage caused by frequent freezing and thawing cycles. Therefore, it is advisable to handle the product with care to ensure its long-term effectiveness.
Storage buffer	Rabbit IgG is stored in a solution of phosphate buffered saline with a pH of 7.4. The solution also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. For optimal preservation, it should be kept at a temperature of -20 °C. This product has a shelf life of 12 months starting from the date of receipt.
Target
Background	Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.
Tissue specificity	Expressed in neuroblastoma, brain and adrenal gland.
Celluar localization	Nucleus;
UniPort	Q99453