Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-PALLD Polyclonal Antibody#abs139251

Please note that the price mentioned above is only for your reference. For detailed information about the price, kindly get in touch with our seller Vecent. It is important to get in touch with our seller for the precise pricing information. Western blot analysis PALLD using HepG2 whole cell...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs139251-100ug	1-2 Weeks	301.0
abs139251-50ug	1-2 Weeks	201.0

Overview
catalog	abs139251
Other names	MYN, also known as Palladin cytoskeletal associated protein or Palld, is encoded by the KIAA0992 gene and is a sarcoma antigen referred to as NY SAR 77. Additionally, this protein is also recognized as PNCA1 or Stx13bp1. MYN is crucial for the formation of stress fibers, actin filaments, and cell adhesion. It also plays a vital role in the organization of the cytoskeleton and cellular migration. The function of MYN has a significant impact on the behavior of cells during cancer development, wound healing, and tissue remodeling.
Source	Rabbit
Specificity	The PALLD Antibody is capable of detecting total PALLD levels that are naturally occurring within the body. To generate similar content, the original text has been rephrased to convey the same message in a different manner.
Species Reactivity	Human;Mouse
Predictive reaction species	Rabbit;Dog;Horse
Antigen	PALLD
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human PALLD.
MW	151kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was used for peptide affinity chromatography to purify the antiserum. This process ensured that the antiserum was highly purified and obtained through a specific and efficient process.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure that the storage temperature remains at -20 °C for a duration of one year and ensure to prevent any repetition of freeze/thaw cycles.
Storage buffer	This Rabbit IgG solution is formulated in phosphate buffered saline, pH 7.4, with the addition of 150mM NaCl, 0.02% sodium azide, and 50% glycerol for stability and long-term storage at -20 °C. It is guaranteed to be stable for 12 months from the date of receipt.
Target
Background	Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci.
Tissue specificity	Detected in both muscle and non-muscle tissues. High expression in prostate, ovary, colon, and kidney. Not detected in spleen, skeletal muscle, lung and peripheral blood lymphocytes (at protein level). Protein is overexpressed in FA6, HPAF, IMIM-PC2, SUIT-2 and PancTu-II sporadic pancreatic cancer cell lines.
Posttranslational modification	Phosphorylated predominantly on serines and, to a lesser extent, on tyrosines (By similarity). Phosphorylation at Ser-1118 by PKB/AKT1 modulates cytoskeletal organization and cell motility.
Celluar localization	Cytoskeleton;Cytosol;Nucleus;Plasma Membrane;
UniPort	Q8WX93