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Rabbit Anti-PRRX2 Polyclonal Antibody#abs139249

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Description

Catalog-specification	Delivery time	USD price
abs139249-100ug	1-2 Weeks	301.0
abs139249-50ug	1-2 Weeks	201.0

Overview
catalog	abs139249
Other names	Homeobox transcription factors are crucial for embryonic development and cell differentiation. One such factor is Paired Mesoderm Homeobox Protein 2 (PMX2), also known as Paired Related Homeobox Protein 2 or Paired-like Homeobox Gene 2. PMX2, alternatively referred to as Paired-like Homeodomain Protein PRX2 or Paired-Related Homeobox Protein 2, plays a significant role in regulating gene expression and controlling various developmental processes. Additionally, PMX2 is sometimes denoted as Predicted NUP98/PRRX2 Fusion Protein, highlighting its potential involvement in genetic fusion events. Its primary gene symbol is Prrx2, and it is commonly identified as PRRX2_HUMAN in genetic databases. The functions of PMX2 are intricately linked to its intricate DNA-binding capabilities and interactions with other transcription factors. It functions as a key regulator of cell fate determination, particularly in mesoderm-derived tissues. PMX2's expression patterns are highly dynamic during embryogenesis, reflecting its essential role in coordinating proper tissue and organ development. In summary, PMX2, with its various aliases such as PRX2, PRX-2, and PRX 2, exemplifies a crucial transcription factor involved in embryonic development and cell differentiation. Its complex regulatory functions and interactions contribute to the precise orchestration of developmental processes.
Source	Rabbit
Specificity	The endogenous levels of total PRRX2 can be effectively detected by the PRRX2 Antibody. By rearranging the provided information, it can be stated that the antibody is capable of accurately identifying the overall concentration of PRRX2 within the biological system.
Species Reactivity	Human;Mouse;Rat
Antigen	PRRX2
Application	The recommended dilutions for Western blot (WB) range from 1:1000 to 1:3000. For immunohistochemistry (IHC), a dilution of 1:200 is suggested. When performing ELISA with a peptide, dilutions of 1:20000 to 1:40000 are recommended.
Immunogen	A synthesized peptide derived from human PRRX2.
MW	27 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purified antiserum underwent peptide affinity chromatography. Please rearrange the provided information to generate highly similar content while ensuring that it is based on the original text.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimum storage conditions, it is recommended to store the product at a temperature of -20 °C for a period of one year. It is important to avoid repeated freeze/thaw cycles, as this can compromise the integrity of the product. Proper storage techniques can help to maintain the quality and effectiveness of the product over time.
Storage buffer	The rabbit IgG comes in a solution of phosphate buffered saline at a pH of 7.4, with 150mM NaCl, 0.02% sodium azide and 50% glycerol. To maintain its stability, it's best stored at -20 °C, and can last up to 12 months from the date of receipt.
Target
Background	May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development.
Tissue specificity	In fetal skin, highest expression found in cells of mesodermal origin within the dermal papilla of the developing hair shaft. Not detected in epidermis or dermis. In adult skin, weakly expressed within the basal layers of the epidermis. Not expressed in dermis.
Celluar localization	Nucleus;
UniPort	Q99811