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Rabbit Anti-P2RX1 Polyclonal Antibody#abs139248

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Description

Catalog-specification	Delivery time	USD price
abs139248-100ug	1-2 Weeks	301.0
abs139248-50ug	1-2 Weeks	201.0

Overview
catalog	abs139248
Other names	The ATP receptor, also known as P2 RX1 or P2X1 receptor, is encoded by the H.sapiens mRNA for ATP receptor. It is a protein referred to as P2RX1 or P2RX1_HUMAN. This receptor belongs to the P2X purinoceptor family and serves as a subunit 1 of the P2X receptor. Its primary function is to act as a ligand-gated ion channel, specifically a purinergic receptor P2X1. It is responsible for transmitting signals upon activation by purinergic ligands.
Source	Rabbit
Specificity	The detection of endogenous levels of total P2RX1 is performed by the P2RX1 Antibody. A similar content can be generated by rearranging the information as follows: The total P2RX1 levels present within the organism are identified using the P2RX1 Antibody.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Horse;Dog;
Antigen	P2RX1
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human P2RX1.
MW	45 kDa
Properties
Concentration	1mg/ml
purification	We employed SulfoLink™ Coupling Resin for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve its quality, keep the product at -20 °C for a period of one year. Make sure to steer clear of subjecting it to repeated freeze/thaw cycles.
Storage buffer	This product contains Rabbit IgG in a solution of phosphate buffered saline, with a pH of 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. To maintain stability, please store this product at -20 °C. It is safe to use for up to 12 months after the receipt date.
Target
Background	Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity).
Celluar localization	Nucleus;Plasma Membrane;
UniPort	P51575