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Rabbit Anti-PE2R4 Polyclonal Antibody#abs135182

Please note that the price mentioned above is for your reference only. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis of extracts from COLO205 cells, using PE2R4 antibody. This product is for research use only, not for use...

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Description

Catalog-specification	Delivery time	USD price
abs135182-100ug	1-2 Weeks	301.0
abs135182-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is for your reference only. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs135182
Other names	EP 4; EP4; EP4R; MGC126583; PE2R4_HUMAN; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostaglandin E receptor 4; Prostaglandin E receptor 4 subtype EP4; Prostaglandin E2 receptor; Prostaglandin E2 receptor EP4 subtype; Prostanoid EP4 receptor; PTGER 2; PTGER 4; PTGER2; PTGER4; are various names and abbreviations used to refer to the same protein or gene. This protein is known as the Prostaglandin E receptor 4, or EP4 for short. It is a subtype of the PGE receptor, specifically responding to Prostaglandin E2 (PGE2). The PTGER2 and PTGER4 are alternate names for this receptor. The MGC126583 and PE2R4_HUMAN are unique identifiers used in scientific research to refer to this specific protein. Overall, these names and terms describe the same protein, the Prostaglandin E2 receptor EP4 subtype, or simply the EP4 receptor. It plays a crucial role in mediating the effects of Prostaglandin E2 in various biological processes.
Source	Rabbit
Specificity	Total levels of endogenous PE2R4 can be detected by the PE2R4 Antibody. The antibody specifically targets PE2R4 protein and can accurately measure the amount of PE2R4 present in a sample. This information is valuable in studying the biological functions and signaling pathways of PE2R4.
Species Reactivity	Human
Predictive reaction species	Sheep;Bovine;
Antigen	PE2R4
Application	For Western blotting, the recommended dilution range is 1:500 to 1:1000. When performing immunofluorescence or immunocytochemistry, use 1:100 to 1:500 dilutions. For ELISA assays using peptides, we suggest diluting at 1:20000 to 1:40000. Please note that these dilution ranges are based on original text information and should be followed for optimal results in your experiments.
Immunogen	A synthesized peptide.
MW	55 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we were able to purify the antiserum through peptide affinity chromatography. This process allowed for the separation of target peptides, resulting in a highly purified antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to store the item at a temperature of -20°C for a duration of one year, taking care to avoid any instances of repeated freeze-thaw cycles. It is important to adhere to these storage instructions to ensure the optimal quality and longevity of the product.
Storage buffer	This Rabbit IgG comes in a solution containing phosphate-buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It must be stored at -20°C and remains stable for 12 months from the date of receipt. The solution is designed to maintain the quality and stability of the IgG, ensuring that it remains effective over the course of its shelf life. The glycerol component also aids in preserving the integrity of the solution, protecting it from freeze-thaw cycles that could cause degradation. All in all, this Rabbit IgG solution is a reliable and convenient option for researchers and scientists looking to work with high-quality antibodies.
Target
Background	Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Tissue specificity	High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.
Posttranslational modification	Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention.
Celluar localization	Plasma Membrane;
UniPort	P35408