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Rabbit Anti-MNDA Polyclonal Antibody#abs141270

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Description

Catalog-specification	Delivery time	USD price
abs141270-100ug	1-2 Weeks	301.0
abs141270-50ug	1-2 Weeks	201.0

Overview
catalog	abs141270
Other names	Myeloid cell nuclear differentiation antigen (MNDA), also known as MNDA_HUMAN and PYHIN3, is a protein encoded by the OTTHUMP00000024384 gene. MNDA is involved in myeloid cell differentiation and plays an important role in the immune system. Its function is to regulate gene expression and promote the development of myeloid cells. MNDA is a crucial factor in maintaining the functionality and integrity of the immune system.
Source	Rabbit
Specificity	Endogenous levels of total MNDA can be detected with the MNDA Antibody.
Species Reactivity	Human
Antigen	MNDA
Application	The dilution range for Western Blot is 1:500 to 1:1000, for IF/ICC it is 1:100 to 1:500, and for ELISA using peptide, it is 1:20000 to 1:40000. Please rearrange the given information to generate a highly similar content while ensuring that the context remains the same.
Immunogen	A synthesized peptide.
MW	46 KD
Properties
Concentration	1mg/ml
purification	Utilizing SulfoLink™ Coupling Resin, peptide affinity chromatography was employed to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure maximum shelf life, it is recommended to store the product in a freezer at a temperature of -20°C for a period of one year. It is advised to avoid subjecting the product to repeated freezing and thawing cycles as this may adversely affect its quality.
Storage buffer	The storage condition for Rabbit IgG is in a solution containing phosphate buffered saline with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C. This product maintains its stability for a period of 12 months from the date of receipt.
Target
Background	In the myeloid lineage, it is possible for this protein to act as both a transcriptional activator and repressor. Its involvement in the granulocyte/monocyte specific response to interferon has also been established. Additionally, it has been observed to enhance the DNA binding ability of YY1, which is a transcriptional repressor protein.
Tissue specificity	Expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appear in myeloblast cells in some cases of acute myeloid Leukemia.
Celluar localization	Extracellular region or secreted;Lysosome;Nucleus;
UniPort	P41218