Rabbit Anti-LAMP1 Polyclonal Antibody#abs135108

Rabbit Anti-LAMP1 Polyclonal Antibody#abs135108

Dear customers, Please note that the price provided above is for your reference only. For detailed pricing information, we kindly ask you to get in touch with our seller Vecent. Thank you for your understanding. If you have any further questions or require assistance, feel free to reach out to...

Description

Catalog-specificationDelivery timeUSD price

abs135108-100ug

1-2 Weeks

301.0

abs135108-50ug

1-2 Weeks

201.0

Dear customers,
Please note that the price provided above is for your reference only. For detailed pricing information, we kindly ask you to get in touch with our seller Vecent.
Thank you for your understanding. If you have any further questions or require assistance, feel free to reach out to us.
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Overview

catalog

abs135108
Other namesLAMP 1, also known as CD107 antigen like family member A or CD107a, is a glycoprotein found on the lysosomal membrane. It is encoded by the LAMP1 gene and is responsible for the proper functioning of lysosomes. LAMP 1 is a large molecule with a molecular weight of 120KD and plays a crucial role in maintaining lysosomal integrity and promoting cellular processes.
LAMP 1, also referred to as CD107 antigen-like family member A or CD107a, is a protein that can be found on the surface of lysosomes. It is encoded by the LAMP1 gene and is also known as Lysosome-associated membrane glycoprotein 1 or Lysosome-associated membrane protein 1. LAMP 1, also called LGP120 or lgpA, is involved in various cellular functions and is essential for the proper functioning of lysosomes.
LAMP 1, or CD107a antigen, is a glycoprotein called Lysosomal Associated Membrane Protein 1. It is encoded by the LAMP1 gene and is also referred to as Lysosome associated membrane glycoprotein 1 or Lysosome-associated membrane protein 1. LAMP 1, also known as LGP120 or lgpA, is a crucial component of lysosomes, which are responsible for the breakdown of cellular waste materials. Its presence on the lysosomal membrane ensures the efficient functioning of lysosomes and supports various cellular processes.
SourceRabbit
SpecificityThe detection of total LAMP1 is possible with the LAMP1 Antibody, which is designed to specifically target the endogenous levels of this protein.
Species ReactivityHuman
AntigenLAMP1
ApplicationThe recommended dilution for WB is between 1:500 to 1:1000, while IF/ICC requires a dilution of 1:100 to 1:500. For ELISA using peptide, the suggested dilution range is 1:20000 to 1:40000. It is important to follow the recommended dilution range to ensure optimal results.
ImmunogenA synthesized peptide.
MW125 KD
Properties

Concentration

1mg/ml

purificationThe SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography in order to purify the antiserum.
ClonalityPolyclonal Antibody
Stability & StorageIt is recommended to store the product at -20 °C for a duration of one year. To maintain its quality, it is important to avoid subjecting it to repeated freeze/thaw cycles.
Storage bufferStore Rabbit IgG at -20 °C in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This product is stable for 12 months from the date of receipt.

Target

Background

Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.

Posttranslational modificationO- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans. The glycosylation of N-76 is essential for Lassa virus entry into cells.
Celluar localizationCytosol;Endosome;Extracellular region or secreted;Lysosome;Plasma Membrane;
UniPortP11279


Western blot analysis of extracts from K562, Jurkat, HepG2, HuvEc, HeLa and COLO205 cells, using LAMP1 antibody.

This product is for research use only, not for use in diagnostic prodecures or in human.


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