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Rabbit Anti-INPP4A Polyclonal Antibody#abs137350

Please note that the price provided above is for your reference only. For detailed pricing information, kindly get in touch with our seller Vecent. Western blot analysis INPP4A using HeLa whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specification	Delivery time	USD price
abs137350-100ug	1-2 Weeks	301.0
abs137350-50ug	1-2 Weeks	201.0

Please note that the price provided above is for your reference only. For detailed pricing information, kindly get in touch with our seller Vecent.

Overview
catalog	abs137350
Other names	The protein 107kDa, which is also known as Inositol polyphosphate 4-phosphatase type I, has various alternative names including 4-bisphosphate 4-phosphatase, INPP4, Inpp4a, and Type I inositol 3,4 bisphosphate 4 phosphatase. It is encoded by genes such as 9630012D15, D130048C09Rik, and TVAS1. The protein plays a crucial role in the dephosphorylation of inositol phosphates, which are signaling molecules involved in multiple cellular processes. Several known functions of the protein include the regulation of insulin secretion, Akt signaling, and cell growth. It is known that the protein interacts with various partners, including PI3K, FAK, and Cofilin, to modulate a multitude of cellular pathways. The clinical significance of the protein is related to its implication in cancer and neurodegenerative disease. Dysregulation of this protein has been linked to various types of cancer, including breast and ovarian cancer. Therefore, the protein is a potential target for future cancer therapy development.
Source	Rabbit
Specificity	The INPP4A Antibody is capable of detecting the total amount of endogenous INPP4A present in a sample. This means that the antibody is able to recognize all forms of INPP4A that are naturally present in the sample. Generating content based on this information can involve rephrasing the original text in a similar way, while keeping the main message intact.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Chicken;Rabbit;Pig;Dog;Sheep;Horse;Bovine
Antigen	INPP4A
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human INPP4A.
MW	110 kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was utilized to perform peptide affinity chromatography and purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to store at a temperature of -20 °C for a duration of one year. Repeated freeze/thaw cycles should be avoided.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-bisphosphate.
Tissue specificity	Isoform 1 is expressed in the platelets, MEG-01 megakaryocytes and Jurkat T-cells. Isoform 2 is expressed in the brain.
Celluar localization	Cytosol;
UniPort	Q96PE3