Rabbit Anti-COX5A Polyclonal Antibody#abs140640

Rabbit Anti-COX5A Polyclonal Antibody#abs140640

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Description

Catalog-specificationDelivery timeUSD price

abs140640-100ug

1-2 Weeks

301.0

abs140640-50ug

1-2 Weeks

201.0

Please note that the price mentioned above is only for your reference. If you require detailed information about the pricing, kindly get in touch with our sales representative Vecent. It's important to note that the content generated should be based on the original text information but presented in a significantly different manner using language model generation, and not using ChapGPT.


Overview

catalog

abs140640
Other namesThe human protein COX5A is a crucial subunit of mitochondrial cytochrome c oxidase (COX), which plays a vital role in cellular respiration. COX5A is also known as COX VA, Cytochrome c oxidase subunit 5A, or Cytochrome c oxidase polypeptide Va. It helps in the transfer of electrons from cytochrome c to oxygen, converting them into water in the final step of electron transport chain. COX5A is encoded by the COX5A gene and is located in the inner mitochondrial membrane. The dysfunction of COX5A has been linked to various mitochondrial diseases and respiratory chain disorders.
SourceRabbit
SpecificityThe COX5A Antibody is capable of detecting the complete amount of COX5A that is naturally present within the body. The levels of COX5A detected by this antibody are entirely endogenous.
Species ReactivityHuman;Mouse;Rat
AntigenCOX5A
ApplicationThe dilution ratios for Western blot range from 1:500 to 1:1000. For immunohistochemistry, the dilution ranges from 1:50 to 1:200. Immunofluorescence and immunocytochemistry require dilutions of 1:100 to 1:500. As for ELISA using peptide, the recommended dilution is between 1:20000 and 1:40000. It is important to note that these dilution ratios are crucial for obtaining accurate and reliable results in these experimental techniques.
ImmunogenA synthesized peptide.
MW17 KD
Properties

Concentration

1mg/ml

purificationWe employed SulfoLink™ Coupling Resin for peptide affinity chromatography to purify the antiserum.
ClonalityPolyclonal Antibody
Stability & StorageTo ensure the preservation of the product, it is recommended to store it at -20 °C for a period of one year. In order to maintain its quality, it is important to avoid subjecting it to repeated freeze/thaw cycles.
Storage bufferStore the Rabbit IgG in a solution of phosphate buffered saline with a pH of 7.4. The solution should contain 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store the IgG at a temperature of -20 °C. The product has a stable shelf life of 12 months from the date of receipt.

Target

Background

This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Celluar localizationExtracellular region or secreted;Mitochondrion;
UniPortP20674


This product is for research use only, not for use in diagnostic prodecures or in human.


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