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Rabbit Anti-ALS2CR16 Polyclonal Antibody#abs138725

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Description

Catalog-specification	Delivery time	USD price
abs138725-100ug	1-2 Weeks	301.0
abs138725-50ug	1-2 Weeks	201.0

Overview
catalog	abs138725
Other names	NBEAL1, also known as Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 17 or ALS2CR17, is a crucial protein involved in the neurodevelopment of individuals. Its role in the pathogenesis of amyotrophic lateral sclerosis 2 (juvenile) has been extensively studied. Another protein, ALS2CR16, is also implicated in the same pathway, contributing to the development and progression of this devastating disease. Moreover, an interesting candidate gene located in the chromosomal region associated with juvenile amyotrophic lateral sclerosis 2 is A530083I02Rik. Detailed investigations are being conducted to understand its exact function and its potential implications in the disease's onset and progression. In addition to their involvement in ALS2, these genes have been linked to other significant biological processes. For instance, NBEAL1 is known for its role in regulating neuronal functions and synaptic plasticity. It bears resemblance to neurobeachin, another protein involved in the same neuronal processes. Furthermore, NBEAL1 shares similarities with beach, FLJ26555, MGC164581, MGC168834, and OTTHUMP00000205117, further highlighting its importance in various cellular activities. Overall, the collective knowledge surrounding these genes and proteins aids in understanding the complex mechanisms underlying amyotrophic lateral sclerosis 2 and sheds light on potential therapeutic targets for the treatment of this devastating disease.
Source	Rabbit
Specificity	The ALS2CR16 Antibody is capable of detecting the total levels of endogenous ALS2CR16. You can rearrange this information to say that ALS2CR16 levels present naturally within the body can be identified using the ALS2CR16 Antibody.
Species Reactivity	Human
Antigen	ALS2CR16
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human ALS2CR16.
MW	307kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was employed for the purification of the antiserum through peptide affinity chromatography. Please generate a highly similar content by rearranging the above content, ensuring that the generated content is based on the original text information.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to keep the material at a temperature of -20 °C for a period of one year. It is important to avoid frequent freezing and thawing cycles, as this may compromise the integrity and quality of the sample. Therefore, it is advisable to handle the material with care and only thaw it when necessary, minimizing the number of cycles. Proper storage and handling can help maintain the stability and longevity of the sample, ensuring accurate and reproducible results.
Storage buffer	This product contains Rabbit IgG in a solution of phosphate buffered saline at pH 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store the product at -20 °C. The product is stable for a period of 12 months from the date of receipt.
Target
Tissue specificity	Highly expressed in brain, kidney, prostate and testis. Weakly expressed in ovary, small intestine, colon and peripheral blood leukocytes. May be correlative to several tumors, such as ovary serous adenocarcinoma and metastasis mammary gland carcinoma breast.
UniPort	Q6ZS30