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Rabbit Anti-IMPDH2 Polyclonal Antibody#abs136803

Please note that the price provided is for reference only. For detailed pricing information, kindly reach out to our seller, Vecent. We recommend contacting Vecent for accurate pricing details. Western blot analysis of extracts of various celllines, using IMPDH2 antibody. This product is for...

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Description

Catalog-specification	Delivery time	USD price
abs136803-100ug	1-2 Weeks	301.0
abs136803-50ug	1-2 Weeks	201.0

Please note that the price provided is for reference only. For detailed pricing information, kindly reach out to our seller, Vecent. We recommend contacting Vecent for accurate pricing details.

Overview
catalog	abs136803
Other names	2,3-Dibromoindophenol; 2,3-Diphenyl-5-methyl-1H-pyrazol-4-ylamine; 5,5'-Dimethyl-2,2'-bipyridine; Chrysazin; Cryptotanshinone; Cryptotanshinone hydrate; Indacenodithiophene; Malvidin-3-O-glucoside; N,N'-Bis(2,6-diisopropylphenyl)-(R,R)-diamino-BINOL; Pinosylvin; Retinyl palmitate; Riboflavin; Riboflavin 5'-phosphate sodium; Riboflavin phosphate sodium; Sinapinic acid; Tungsten carbide
Source	Rabbit
Specificity	The total IMPDH2 levels within cells can be accurately detected using the IMPDH2 Antibody, allowing for the measurement of endogenous levels. Making use of this antibody, researchers can analyze the overall IMPDH2 expression and activity in various biological samples. This antibody specifically targets IMPDH2, providing reliable and specific detection of this protein. By utilizing this antibody, scientists gain valuable insights into the regulation and function of IMPDH2 in cellular processes.
Species Reactivity	Human;Mouse;Rat
Antigen	IMPDH2
Application	For Western blot analysis, a dilution range of 1:500 to 1:2000 is recommended, while for immunohistochemistry, a dilution range of 1:50 to 1:200 is suggested. For ELISA using peptide as a target, a dilution range of 1:20000 to 1:40000 is ideal. It is important to note that these dilutions may vary depending on the specific experimental conditions and the nature of the sample being tested. Therefore, it is always recommended to optimize the dilution factors for each individual experiment to obtain the best possible results.
Immunogen	A synthesized peptide derived from human IMPDH2.
MW	55kDa
Properties
Concentration	1mg/ml
purification	To obtain a purified antiserum, peptide affinity chromatography was used which involved the application of SulfoLink™ Coupling Resin.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20°C for up to one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles as this could lead to a decline in its effectiveness. It is therefore essential to ensure proper storage conditions are maintained at all times to ensure the longevity of the product.
Storage buffer	The Rabbit IgG comes in a solution of phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide and 50% glycerol. It should be stored at a temperature of -20 °C and will remain stable for a period of 12 months after its receipt. It is important to follow these storage instructions to ensure that the Rabbit IgG stays viable and effective for use.
Target
Background	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Tissue specificity	IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
Posttranslational modification	The N-terminus is blocked.
Celluar localization	Cytosol;Extracellular region or secreted;Nucleus;Peroxisome;
UniPort	P12268