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Rabbit Anti-PITX1 Polyclonal Antibody#abs133526

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Description

Catalog-specification	Delivery time	USD price
abs133526-100ug	1-2 Weeks	301.0
abs133526-50ug	1-2 Weeks	201.0

Overview
catalog	abs133526
Other names	The gene known as PITX1 is also referred to by various other names such as BFT, CCF, Hindlimb expressed homeobox protein backfoot, LBNBG, Paired like homeodomain 1, Paired like homeodomain transcription factor 1, Pituitary homeo box 1, Pituitary homeobox 1, Pituitary otx related factor, and PTX1. It is a transcription factor that plays a crucial role in embryonic development, particularly in the formation of hindlimbs. PITX1 is known to regulate the expression of genes involved in limb morphogenesis. The protein encoded by this gene contains a homeodomain, which is a DNA-binding domain that allows it to bind to specific DNA sequences and regulate the transcription of target genes. The exact function of PITX1 in limb development is not completely understood, but studies have shown that mutations in this gene can lead to brachydactyly, a condition characterized by the shortening or fusion of fingers or toes. Understanding the roles and regulation of PITX1 is important for gaining insights into limb development and related disorders.
Source	Rabbit
Specificity	Endogenous levels of total PITX1 can be effectively identified using the PITX1 Antibody. Please rearrange the content to create a highly similar but different statement based on the original text information.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Zebrafish;Chicken;Pig;Dog;Horse;Bovine;Sheep;
Antigen	PITX1
Application	WB1:5001:1000，IF/ICC1:1001:500，ELISA(peptide)1:200001:40000。。
Immunogen	A synthesized peptide.
MW	34 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was employed to purify the antiserum. The process resulted in the isolation of a highly purified form of the antiserum, which can be utilized for further experiments and analyses. This technique is proven to be effective in removing impurities and contaminants, ensuring the quality of the final product. With the help of this method, researchers can obtain a reliable and accurate result, which is essential in maintaining the integrity of their work.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is crucial to avoid subjecting the item to repeated freeze/thaw cycles during this storage period.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.
Celluar localization	Nucleus;
UniPort	P78337