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Rabbit Anti-Pmp24 Polyclonal Antibody#abs140517

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Description

Catalog-specification	Delivery time	USD price
abs140517-100ug	1-2 Weeks	301.0
abs140517-50ug	1-2 Weeks	201.0

Overview
catalog	abs140517
Other names	Peroxisomal membrane protein 4, also known as PMP24, is an intrinsic membrane protein with a molecular weight of 24 kDa. This protein plays a crucial role in peroxisome function and is specifically located in the peroxisomal membrane. It is referred to as 24kDa peroxisomal intrinsic membrane protein too. PMP24 is involved in various cellular processes, contributing to peroxisome biogenesis and metabolism. Its presence and function are essential for maintaining the integrity and optimal functioning of peroxisomes within the cell.
Source	Rabbit
Specificity	The Pmp24 Antibody is able to identify total Pmp24 at the endogenous levels. The information provided in the original text has been reorganized to generate a similar statement.
Species Reactivity	Human;Mouse
Predictive reaction species	Pig;Sheep;Dog;Horse;
Antigen	Pmp24
Application	For western blotting, a dilution of 1:1000 is recommended. When using immunofluorescence or immunocytochemistry techniques, a dilution range of 1:100 to 1:500 is optimal. In ELISA assays utilizing peptide substrates, a dilution range of 1:20000 to 1:40000 is appropriate. It is important to note that these dilution ranges are based on the original text information and should be followed closely for accurate results.
Immunogen	A synthesized peptide derived from human Pmp24.
MW	24kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. Similar content can also be generated by stating that the purification process utilized peptide affinity chromatography with SulfoLink™ Coupling Resin to obtain a pure antiserum. It is important to maintain the accuracy and key details of the original text while rephrasing to avoid changing its intended meaning.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the preservation of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. To maintain its quality, it is important to avoid subjecting the product to repeated freeze and thaw cycles.
Storage buffer	This product contains Rabbit IgG that has been formulated in phosphate buffered saline at pH 7.4, with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. For optimal stability, it is recommended to store the product at a temperature of -20 °C. This product has a shelf life of 12 months from the date of receipt, ensuring dependable quality assurance.
Target
Background	Hypermethylation-mediated silencing of PXMP4 may be involved in prostate carcinogenesis. PXMP4 undergoes hypermethylation and silencing during the transition of prostate adenocarcinoma cells from androgen dependence to androgen independence.
Tissue specificity	Expressed in normal prostate epithelial cells, and androgen-sensitive prostate adenocarcinoma cells. Not expressed in androgen-insensitive prostate adenocarcinoma cells.
Celluar localization	Peroxisome;
UniPort	Q9Y6I8