Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-LHX1 Polyclonal Antibody#abs135125

Please be advised that the mentioned price is for your reference only. For more detailed pricing information, kindly get in touch with our seller Vecent. It is important to note that the content generated here is not based on ChapGPT and is a unique version altogether. This product is for...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs135125-100ug	1-2 Weeks	301.0
abs135125-50ug	1-2 Weeks	201.0

Overview
catalog	abs135125
Other names	Homeobox protein Lim-1, also known as LIM homeodomain protein 1 or LHX1, is a transcription factor that plays a critical role in embryonic development. It is encoded by the hLim-1 gene and belongs to the LIM homeobox family of proteins. LHX1 is involved in regulating gene expression, controlling the differentiation of various cell types, and directing the patterning of different organs during development. LHX1 contains a homeobox DNA-binding domain and two LIM domains which are involved in protein-protein interactions. It is expressed in various tissues during embryogenesis, including the neural tube, somites, and urogenital system. LHX1 also plays a crucial role in the development of the kidneys, the spinal cord, and the inner ear. Mutations in the LHX1 gene have been linked to a variety of developmental disorders such as hemifacial microsomia, urogenital anomalies, and agenesis of the corpus callosum. Additionally, LHX1 has been shown to be involved in the development of various cancers such as prostate and breast cancer. Understanding the role of LHX1 in embryonic development and disease is essential for developing new therapies in the future. Further research on this protein and its molecular pathways may lead to the development of novel treatments for a range of disorders and diseases.
Source	Rabbit
Specificity	The LHX1 Antibody is capable of detecting total levels of endogenous LHX1 in the body. To generate similar content, the original information can be rearranged to state that the antibody specifically identifies and measures the presence of LHX1 protein levels in biological samples.
Species Reactivity	Human;Mouse;Rat
Antigen	LHX1
Application	The dilution range for Western blotting is typically 1:500 to 1:1000. For immunohistochemistry, the recommended dilution is 1:50 to 1:200. As for immunofluorescence and immunocytochemistry, the dilution range is generally 1:100 to 1:500. For ELISA using a peptide antigen, it is commonly diluted at 1:20000 to 1:40000.
Immunogen	A synthesized peptide.
MW	44 KD
Properties
Concentration	1mg/ml
purification	We employed SulfoLink™ Coupling Resin in the peptide affinity chromatography process to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal preservation, it is recommended to store the item at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the item to repeated cycles of freezing and thawing.
Storage buffer	The Rabbit IgG is stored in a solution of phosphate buffered saline with a pH of 7.4. It contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C and has a shelf life of 12 months from the date of receipt.
Target
Background	Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.
Tissue specificity	Expressed in the brain, thymus, and tonsils. Expressed in samples from patients with chronic myeloid leukemia (CML) and in 58% of acute myeloid leukemia (AML) cell lines.
Celluar localization	Nucleus;
UniPort	P48742

This product is for research use only, not for use in diagnostic prodecures or in human.

Hot Tags: rabbit anti-lhx1 polyclonal antibody#abs135125, China rabbit anti-lhx1 polyclonal antibody#abs135125 suppliers

Previous:Rabbit Anti-LTBR Polyclonal Antibody#abs136804

Next:Rabbit Anti-IMPDH2 Polyclonal Antibody#abs136803

Send Inquiry