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Rabbit Anti-ILRL2 Polyclonal Antibody#abs138507

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Description

Catalog-specification	Delivery time	USD price
abs138507-100ug	1-2 Weeks	301.0
abs138507-50ug	1-2 Weeks	201.0

Dear valued customer,
Please note that the price mentioned above is for reference purposes only. For accurate pricing information, please contact our seller, Vecent. We are committed to providing you with the best possible service and competitive pricing to meet your needs.
Thank you for your interest in our products and we look forward to hearing from you soon.
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Overview
catalog	abs138507
Other names	IL 1 receptor related protein 2, also known as IL-36 receptor or IL1RRP2, is a protein that plays an important role in the immune system. It is encoded by the Il1rl2 gene and is a member of the interleukin 1 receptor family. This protein binds to interleukin-36 cytokines and is involved in a variety of inflammatory responses. IL 1 receptor related protein 2 is expressed in many tissues, including the skin, lungs, and joints. It has been implicated in the development of autoimmune diseases and is a potential target for drug development. Overall, IL 1 receptor related protein 2 is an important component of the immune system and plays a critical role in regulating inflammation and immune responses.
Source	Rabbit
Specificity	The endogenous levels of total ILRL2 can be detected by the ILRL2 Antibody. The content should be generated by rearranging the original text information to ensure high similarity while using a different language model.
Species Reactivity	Human
Antigen	ILRL2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human ILRL2.
MW	65 kDa
Properties
Concentration	1mg/ml
purification	We employed SulfoLink™ Coupling Resin for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality, store the product at a temperature of -20 °C for a duration of one year. It is crucial to avoid subjecting the product to several cycles of freezing and thawing.
Storage buffer	To ensure optimal storage conditions, it is recommended to store Rabbit IgG in phosphate buffered saline (PBS) at a pH of 7.4, supplemented with 150mM NaCl and 0.02% sodium azide. Additionally, the addition of 50% glycerol helps maintain the stability of the antibody. For long-term storage, it is advisable to store the solution at a temperature of -20 °C. It is important to note that the antibody is guaranteed to remain stable for a period of 12 months from the date of receipt.
Target
Background	Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.
Tissue specificity	Expressed in synovial fibroblasts and articular chondrocytes. Expressed in keratinocytes and monocyte-derived dendritic cells. Expressed in monocytes and myeloid dendritic cells; at protein level.
Celluar localization	Plasma Membrane;
UniPort	Q9HB29