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Rabbit Anti-GCNT6 Polyclonal Antibody#abs140910

Please note that the price mentioned above is only for your reference. If you require detailed pricing information, kindly reach out to our seller Vecent. Western blot analysis of extracts from K562 cells and NIH/3T3 cells, using GCNT6 antibody. This product is for research use only, not for use...

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Description

Catalog-specification	Delivery time	USD price
abs140910-100ug	1-2 Weeks	301.0
abs140910-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. If you require detailed pricing information, kindly reach out to our seller Vecent.

Overview
catalog	abs140910
Other names	GCNT6, also known as Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 6 or bA421M1.3, is an enzyme involved in glycosylation processes. This enzyme catalyzes the transfer of N-acetylglucosamine to galactosyl-O-glycosyl-glycoprotein, resulting in the formation of complex glycoproteins. GCNT6 is a human protein encoded by the GCNT6 gene. GCNT6 plays a crucial role in various biological processes, including cell adhesion, signaling, and immune response. It is primarily localized in the Golgi apparatus, where it is responsible for modifying glycoproteins by adding N-acetylglucosamine residues to specific sites. Mutations in the GCNT6 gene have been associated with certain diseases and disorders, including cancer and inflammatory conditions. Studies have shown that dysregulation of GCNT6 activity can lead to aberrant glycosylation patterns, which in turn can affect cellular functions and contribute to disease progression. Understanding the function and regulation of GCNT6 has important implications for biomedical research, as it provides insights into glycosylation mechanisms and potential therapeutic targets. Further studies are needed to elucidate the precise role of GCNT6 and its implications in human health and disease.
Source	Rabbit
Specificity	The total level of endogenous GCNT6 can be detected using the GCNT6 Antibody. Rearranging the content, we can say: The GCNT6 Antibody is capable of detecting the total endogenous levels of GCNT6 in a sample.
Species Reactivity	Human;Mouse
Antigen	GCNT6
Application	The dilution range for Western Blot is suggested to be between 1:500 and 1:1000. For immunofluorescence/immunocytochemistry experiments, the recommended dilution range is 1:100 to 1:500. On the other hand, ELISA using peptide as the antigen necessitates a dilution range of 1:20000 to 1:40000.
Immunogen	A synthesized peptide.
MW	45 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography to achieve purification.
Clonality	Polyclonal Antibody
Stability & Storage	It is advisable to keep the item stored at a temperature of -20 °C for a period of one year. Avoid frequent freezing and thawing cycles to maintain high quality.
Storage buffer	- The Rabbit IgG is stored in a solution of phosphate buffered saline (pH 7.4), containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. - It should be stored at a temperature of -20 °C. - The solution is stable for a period of 12 months from the date of receipt.
Target
Background	Glycosyltransferase.
Celluar localization	Golgi apparatus;
UniPort	Q5T4J0