Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-IL13 Polyclonal Antibody#abs132899

Please note that the price mentioned above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Feel free to reach out to Vecent for accurate price details and any other inquiries you may have. Western blot analysis of IL13...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs132899-50ug	1-2 Weeks	201.0
abs132899-100ug	1-2 Weeks	301.0

Overview
catalog	abs132899
Description	This substance is known as a cytokine, and one of its key functions is to inhibit the production of other inflammatory cytokines. It works in tandem with IL2 to regulate the synthesis of interferon-gamma, which is a crucial component of immune function. This substance plays a crucial role in the regulation of immune and inflammatory responses, and may be an important target for therapeutic interventions.
Other names	Allergic rhinitis, also known as ALRH, is a common condition that causes nasal congestion, itching, and sneezing in response to allergens. It can also be associated with bronchial hyperresponsiveness 1 (BHR1), which is a key feature of bronchial asthma. IL-13, or Interleukin 13, is a cytokine that is involved in the pathophysiology of both ALRH and BHR1. MGC116786, MGC116788, and MGC116789 are all potential gene variants that have been associated with these conditions. NC30 and P600 are other markers that may be used to identify individuals who are at risk for developing allergic rhinitis or bronchial asthma. By understanding the underlying mechanisms of these conditions and targeting them with appropriate treatments, patients can experience significant relief from their symptoms and improve their quality of life.
Source	Rabbit
Specificity	The detection of total IL13 can be achieved using an IL13 antibody, which specifically targets the endogenous levels of IL13. By utilizing this antibody, researchers can accurately measure and evaluate the overall presence of IL13 within a sample or biological system.
Species Reactivity	Human;Mouse
Antigen	IL13
Application	For Western blotting, the recommended dilution range is between 1:500 to 1:2000. When conducting immunohistochemistry, it is suggested to dilute the primary antibody at a range of 1:50 to 1:200. As for ELISA assays, using a peptide substrate, a recommended dilution range of 1:20000 to 1:40000 is recommended for optimal results. By tweaking the concentration of the antibody used, one can ensure the highest quality of immunoreactivity and specificity in their experiments.
Immunogen	A synthesized peptide.
MW	16 kDa
Properties
Concentration	1mg/ml
purification	Purifying the antiserum involved the use of SulfoLink™ Coupling Resin in peptide affinity chromatography. A similar and rearranged content based on the original text could be as follows: "Utilizing SulfoLink™ Coupling Resin in peptide affinity chromatography, we successfully purified the antiserum."
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to multiple freeze/thaw cycles.
Storage buffer	The solution containing Rabbit IgG is composed of phosphate buffered saline with a pH level of 7.4. It also contains 150 millimoles of sodium chloride, 0.02% of sodium azide, and 50% glycerol as a preservative.
Target
Background	Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages (By similarity).
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	P35225