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Rabbit Anti-IL-1R9 Polyclonal Antibody#abs140450

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Description

Catalog-specification	Delivery time	USD price
abs140450-100ug	1-2 Weeks	301.0
abs140450-50ug	1-2 Weeks	201.0

Overview
catalog	abs140450
Other names	IL 1RAPL2, also known as IL-1 receptor accessory protein-like 2 or IL-1R9, is a protein that plays an important role in the immune system. It belongs to the family of interleukin-1 receptors, which are involved in inflammatory responses. IL 1RAPL2 is a three immunoglobulin domain-containing protein. The protein is encoded by the IL1RAPL2 gene, which is located on the X chromosome. Mutations in this gene have been associated with X-linked intellectual disability. IL1RAPL2 is also known as TIGIRR-1 or three immunoglobulin domain-containing IL-1 receptor-related 1. It is essential for the production of cytokines, which are chemical messengers that regulate the immune response. The protein is found in various tissues, including the brain, liver, and kidney. IL1RAPL2 is an important target for the development of new therapies for inflammatory disorders, autoimmune diseases, and cancer.
Source	Rabbit
Specificity	The IL-1R9 Antibody is capable of detecting total levels of endogenous IL-1R9. This means that it can identify the entire amount of IL-1R9 present in a sample, using specific antibodies that bind exclusively to this protein. By detecting the levels of IL-1R9, researchers and clinicians can better understand the immune response, inflammation, and other processes driven by this receptor. The IL-1R9 Antibody is therefore a valuable tool for investigating the role and function of IL-1R9 in various biological contexts.
Species Reactivity	Human;Mouse;Rat
Antigen	IL-1R9
Application	Here are the instructions for dilution ratios for various applications of our product: for Western blotting, please use a dilution ratio of 1:1000; for immunohistochemistry, please use a dilution ratio of 1:200; for immunofluorescence/immunocytochemistry, please use a dilution ratio ranging from 1:100 to 1:500; for ELISA using peptide as the antigen, please use a dilution ratio ranging from 1:20000 to 1:40000. These recommended dilution ratios are based on the optimal performance and sensitivity of our product.
Immunogen	A synthesized peptide derived from human IL-1R9.
MW	79kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was conducted through peptide affinity chromatography. A highly effective method, this allowed for a high degree of purification and optimization of the antiserum for further use.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure maximum shelf life, it is recommended that you store the product at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles, as this can have a negative impact on its quality and effectiveness. By following these storage guidelines, you can ensure that the product remains effective and safe to use for an extended period of time.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Tissue specificity	Detected at low levels in fetal and adult brain, in particular in the frontal lobe, temporal lobe and cerebellum. Detected at very low levels in skin, liver, fetal ovary and in placenta.
Celluar localization	Plasma Membrane;
UniPort	Q9NP60