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Rabbit Anti-HEXIM2 Polyclonal Antibody#abs132827

Description

Catalog-specification	Delivery time	USD price
abs132827-100ug	1-2 Weeks	301.0
abs132827-50ug	1-2 Weeks	201.0

Please note that the price provided is for your reference only. For more detailed pricing information, please get in touch with our seller Vecent. It is important to keep in mind that the generated content should be based on the original text information, but you should use a language model to produce a highly similar content by rearranging the existing text. Avoid simply generating text using ChapGPT and instead, use a different approach to deliver a totally different message.

Overview
catalog	abs132827
Description	This protein is a transcriptional regulator that functions by inhibiting RNA polymerase II transcription. It works in conjunction with 7SK snRNA to sequester P-TEFb within a large, inactive 7SK snRNP complex, which prevents the phosphorylation of RNA polymerase II. This, in turn, prevents transcriptional elongation from occurring.
Other names	The protein known as Hexamethylene bis-acetamide-inducible protein 2, or Hexamthylene bis-acetamide inducible 2, is also commonly referred to as HEXI2_HUMAN or HEXIM2. This protein, sometimes just called L3, plays an important role in cellular function and is induced by certain compounds. HEXIM2 is essential for proper cellular functioning, and its expression can be influenced by a number of factors. Understanding the role of this protein in human biology is an ongoing area of research.
Source	Rabbit
Specificity	Total HEXIM2 levels can be detected using the HEXIM2 antibody, which is capable of identifying endogenous levels of the protein. To create a highly similar content, the information provided in the original text can be rearranged as follows: The HEXIM2 antibody is designed to specifically detect total HEXIM2 levels within the body. By targeting endogenous levels of the protein, it enables researchers to accurately assess the overall expression of HEXIM2. This antibody provides a valuable tool for studying the role and regulation of HEXIM2 in various biological processes.
Species Reactivity	Human;Mouse
Antigen	HEXIM2
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	32 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was achieved through peptide affinity chromatography. As a result, a highly purified antiserum was obtained.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain its potency, it is recommended to store the product at a temperature of -20 °C for a period of one year. Be sure to avoid frequent thawing and refreezing cycles to prevent damage to the product.
Storage buffer	The formulation of the solution includes phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This composition is commonly used for preserving Rabbit IgG in a stable condition. The pH of 7.4 helps maintain the biological activity of the IgG, while the NaCl concentration ensures optimal conditions for the antibody. Sodium azide, at a low concentration of 0.02%, acts as a preservative, preventing microbial growth. Lastly, the inclusion of 50% glycerol facilitates long-term storage by preventing the formation of ice crystals that can damage the IgG molecules. Overall, this formulation provides an ideal environment for the stability and preservation of Rabbit IgG.
Target
Background	Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Tissue specificity	Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed.
Celluar localization	Cytosol;Nucleus;
UniPort	Q96MH2