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Rabbit Anti-ARL11 Polyclonal Antibody#abs132822

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Description

Catalog-specification	Delivery time	USD price
abs132822-100ug	1-2 Weeks	301.0
abs132822-50ug	1-2 Weeks	201.0

Overview
catalog	abs132822
Description	Possibly involved in the initiation of cell death. It has been suggested that this gene could function as a tumour suppressor.
Other names	Protein ARL11, also known as ADP ribosylation factor like 11 or ADP ribosylation factor like tumor suppressor protein 1, is a crucial factor in cellular processes. It is a member of the ADP-ribosylation factor-like protein family and plays a significant role as a tumor suppressor. ARL11, also referred to as ARLTS1 or ARL11_HUMAN, exhibits similarity to ADP ribosylation factors. Its function is crucial in regulating various cellular processes such as intracellular vesicular trafficking, membrane remodeling, and cytoskeleton organization. The identification of ARL11 as a tumor suppressor protein highlights its importance in inhibiting the progression of cancer. Its involvement in cellular activities suggests that dysregulation of ARL11 can contribute to the development of tumors. In summary, ARL11 or ADP ribosylation factor like 11, is a significant tumor suppressor protein that belongs to the ADP-ribosylation factor-like protein family. Its role in cellular processes and potential implications in tumor development make it a promising candidate for further research and understanding its therapeutic potential.
Source	Rabbit
Specificity	The ARL11 antibody is capable of recognizing the entire spectrum of endogenous ARL11 protein levels. This means that it can detect all forms of ARL11 present in the cells or tissues being analyzed. By targeting the total ARL11, the antibody enables precise quantification of this important protein in various biological samples. Its effectiveness in identifying ARL11 underscores its utility in numerous research applications.
Species Reactivity	Human;Rat
Antigen	ARL11
Application	The recommended dilution for Western Blot is between 1:500 to 1:2000, and for Immunohistochemistry it is between 1:50 to 1:200. For ELISA using peptide, the optimal dilution range is 1:20000 to 1:40000. These dilution ranges are crucial to attain accurate and reliable results in these assays. It is recommended to optimize the dilution factor based on the target protein and the specific experimental conditions. Diluting the primary antibody too much can result in weak or non-specific signals, while insufficient dilution can lead to high background signal and false positive readings. Therefore, proper optimization of antibody dilution ensures optimal results and reduces experimental variability.
Immunogen	A synthesized peptide.
MW	21 kDa
Properties
Concentration	1mg/ml
purification	The purification process for the antiserum involved using SulfoLink™ Coupling Resin in peptide affinity chromatography. During this step, the antiserum was carefully purified to remove any impurities and ensure a highly effective end product. By utilizing this specific type of resin, the purification was optimized for maximum efficiency and yield. Overall, this process successfully produced a high-quality antiserum that is ready for use in further experiments and applications.
Clonality	Polyclonal Antibody
Stability & Storage	You should store the item at a temperature of -20 °C for a duration of one year. It is important to prevent the item from undergoing multiple freeze/thaw cycles.
Storage buffer	In a solution of phosphate buffered saline at pH 7.4, with 150mM of NaCl and 0.02% sodium azide, Rabbit IgG can be found. Additionally, this solution contains 50% glycerol to aid in preservation.
Target
Background	May play a role in apoptosis. May act as a tumor suppressor.
Tissue specificity	Expressed in lung and leukocytes.
UniPort	Q969Q4