Rabbit Anti-Interleukin2 Polyclonal Antibody#abs131181

abs131181-50ug

1-2 Weeks

201

abs131181-100ug

1-2 Weeks

301

Description

This crucial protein is essential for regulating the immune response as it is produced by T-cells when they encounter antigenic or mitogenic stimulation. Apart from supporting T-cell proliferation, it also has the capability to stimulate various other cells including B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

Other names

Interleukin-2, also known as IL-2 or IL2, is a vital lymphokine involved in the regulation of T cell clonal expansion. It plays a crucial role as a T cell growth factor, facilitating the proliferation and development of T cells. With its official gene symbol IL2_HUMAN and alternative names like POIL2 and TCGF, this protein is essential for maintaining the robust functioning of the immune system. Aldesleukin is a pharmaceutical form of IL-2 that is commonly used in clinical settings for immune-related therapies. Its involvement in the modulation of T cell clonal expansion highlights the significance of IL-2 in the immune response.

Source

Rabbit

Specificity

The Interleukin 2 Antibody is capable of identifying total Interleukin 2 at its naturally occurring levels within the body. This means that it is sensitive to the presence of both endogenous and exogenous forms of Interleukin 2. Utilizing this antibody provides researchers with a valuable tool for characterizing and studying Interleukin 2-mediated immune responses and pathways.

Predictive reaction species

Horse

Application

ELISA(peptide) 1:20000-1:40000 and WB 1:500-1:2000 are the recommended dilution ranges for the respective assays. The WB assay is typically performed at a higher dilution range compared to the ELISA assay. It is important to note that these dilution ranges may vary depending on the specific experiment and the target protein being studied.

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Properties

1mg/ml

Purification

Using SulfoLink™ Coupling Resin, the purification of the antiserum was conducted through peptide affinity chromatography. Similar content can be created by rephrasing the original text, while retaining the same information and context.

Clonality

Polyclonal Antibody

To keep the product fresh and usable for a longer period of time, it is recommended to store it at a temperature of -20 °C. However, it is important to avoid repeating the process of freezing and thawing as it can affect the quality of the product. It is recommended that the product be stored this way for a period of one year. It is crucial to follow these guidelines to ensure that the product maintains its effectiveness and quality.

Storage buffer

This product contains Rabbit IgG in a solution of phosphate buffered saline, pH 7.4, with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this item at a temperature of -20 °C, and it is stable for 12 months from the date of receipt. Please be sure to handle this product with care and follow all recommended storage guidelines for optimal performance and longevity.

Target

Background

This crucial protein is produced by T-cells in response to antigenic or mitogenic stimulation. It plays a vital role in regulating the immune response by promoting T-cell proliferation and facilitating various other activities. Additionally, it has the ability to stimulate diverse cell types including B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

Celluar localization

P60568