Rabbit Anti-LY75 Polyclonal Antibody#abs135112
Please note that the price mentioned here is for your reference only. If you require more detailed pricing information, please contact our seller Vecent. It is important to keep in mind that the actual price may vary depending on various factors. Therefore, we strongly recommend getting in touch...
Description
| Catalog-specification | Delivery time | USD price |
abs135112-100ug | 1-2 Weeks | 301.0 |
abs135112-50ug | 1-2 Weeks | 201.0 |
Please note that the price mentioned here is for your reference only. If you require more detailed pricing information, please contact our seller Vecent. It is important to keep in mind that the actual price may vary depending on various factors. Therefore, we strongly recommend getting in touch with our seller for a more accurate understanding of the pricing structure. Thank you for your interest in our products and services.
| Overview | |
catalog | abs135112 |
| Other names | The antigen known as C-type lectin domain family 13 member B, also referred to as CD205 or DEC-205, is a protein encoded by the LY75 gene in humans. It is commonly found on the surface of certain cells, including lymphocytes and renal cell carcinoma cells. This antigen is also sometimes called gp200 or gp200 MR6. CD205 plays a role in immune responses and is involved in the recognition and uptake of antigens by antigen-presenting cells. Its presence has been linked to the pathogenesis of renal cell carcinoma. LY75, or lymphocyte antigen 75, is the official gene name for this protein. |
| Source | Rabbit |
| Specificity | Total LY75 levels can be measured using the LY75 Antibody, which is designed to detect endogenous LY75. |
| Species Reactivity | Human;Mouse |
| Antigen | LY75 |
| Application | The dilution ratio for Western Blot (WB) is 1:500 to 1:1000, for Immunofluorescence/Immunocytochemistry (IF/ICC) is 1:100 to 1:500, and for ELISA (peptide) is 1:20000 to 1:40000. It is essential to rearrange the content to maintain the accuracy of the information. |
| Immunogen | A synthesized peptide. |
| MW | 200 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | Using SulfoLink™ Coupling Resin, the antiserum was purified through peptide affinity chromatography. It was a meticulous process that resulted in a highly purified and concentrated antiserum solution. The resin efficiently captured the targeted antigenic peptides and was eluted to release the desired antibodies. This purification technique is preferred because it produces high yields and purity. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To ensure proper storage, keep the product at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles. |
| Storage buffer | The rabbit IgG comes in a solution of phosphate buffered saline with a pH of 7.4, containing 150mM of NaCl and 0.02% sodium azide, as well as 50% glycerol to maintain stability. To keep the solution viable, it should be stored at -20 °C, where it will remain stable for up to 12 months from the date of receipt. |
Target | |
Background | Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes. |
| Tissue specificity | Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. |
| Posttranslational modification | N-glycosylated. |
| Celluar localization | Extracellular region or secreted;Plasma Membrane; |
| UniPort | O60449 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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